Phosphorylation of NLRC4 is critical for inflammasome activation
17:36 EDT 12 Aug 2012 | Nature Publishing
NLRC4 is a cytosolic member of the NOD-like receptor family that is expressed in innate immune cells. It senses indirectly bacterial flagellin and type III secretion systems, and responds by assembling an inflammasome complex that promotes caspase-1..
Original Article: Phosphorylation of NLRC4 is critical for inflammasome activation
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