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Endogenous antigen tunes the responsiveness of naive B cells but not T cells

17:40 EDT 19 Aug 2012 | Nature Publishing

In humans, up to 75% of newly generated B cells and about 30% of mature B cells show some degree of autoreactivity. Yet, how B cells establish and maintain tolerance in the face of autoantigen exposure during and after development is not certain. Stu..

Original Article: Endogenous antigen tunes the responsiveness of naive B cells but not T cells

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