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Rapid induction of inflammatory lipid mediators by the inflammasome in vivo

17:40 EDT 19 Aug 2012 | Nature Publishing

Detection of microbial products by host inflammasomes is an important mechanism of innate immune surveillance. Inflammasomes activate the caspase-1 (CASP1) protease, which processes the cytokines interleukin (IL)-1β and IL-18, and initiates a lytic..

Original Article: Rapid induction of inflammatory lipid mediators by the inflammasome in vivo

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