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EPHA4 is a disease modifier of amyotrophic lateral sclerosis in animal models and in humans

15:51 EDT 26 Aug 2012 | Nature Publishing

Epha4 is a receptor involved in axonal repulsion. Wim Robberecht and his colleagues report that genetic or pharmacological inhibition of Epha4 is protective in rodent and zebrafish models of amyotrophic lateral sclerosis. In humans, expression of Eph..

Original Article: EPHA4 is a disease modifier of amyotrophic lateral sclerosis in animal models and in humans

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