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The histone chaperone Spt6 coordinates histone H3K27 demethylation and myogenesis

15:01 EDT 15 Mar 2013 | Nature Publishing

The chaperone Spt6 promotes myogenesis by counteracting Polycomb-mediated gene silencing through the promotion of UTX-dependent H3K27 demethylation at muscle-specific genes.

Original Article: The histone chaperone Spt6 coordinates histone H3K27 demethylation and myogenesis

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