Structural basis for molecular recognition of folic acid by folate receptors

22:11 EDT 14 Jul 2013 | Nature Publishing

Folate receptors (FRα, FRβ and FRγ) are cysteine-rich cell-surface glycoproteins that bind folate with high affinity to mediate cellular uptake of folate. Although expressed at very low levels in most tissues, folate receptors, especially FRα, ar...

Original Article: Structural basis for molecular recognition of folic acid by folate receptors

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