Track topics on Twitter Track topics that are important to you
Sunderland, UK, 18 October 2016: Arquer Diagnostics Ltd (Arquer), a diagnostic company which has developed a high sensitivity, high specificity, ELISA-based urine test for cancer, today announced that it has signed a collaboration agreement with the University of Sunderland. The partnership aims to investigate non-invasive specimen preparation techniques, which will facilitate the use of Arquer’s MCM5-ELISA test in a wider range of cancers.
Arquer’s MCM5-ELISA is a simple, non-invasive test, which has been developed to accurately diagnose both bladder and prostate cancer. The test works by detecting the presence of minichromosome maintenance complex component 5 (MCM5) protein, a marker for the presence of dividing cancer cells, in urine. MCM proteins are directly involved in cell replication, and are shed into urine by both prostate and bladder tumours. Through the partnership with the University of Sunderland, Faculty of Applied Sciences, Arquer aims to identify the optimal conditions for processing various samples collected using different collection methods to assist in the preparation of a clinical feasibility study in a wider range of cancers.
As part of the collaboration, the University will be carrying out in vitro work, using cell lines, to optimise non-invasive sample collection methods which may be compatible with the MCM5-ELISA. Arquer will supply the MCM5-ELISA tests to enable the University to test the effectiveness of the sampling methods. The study is expected to conclude in early 2017.
Commenting on the partnership, Mr Tristan Sillars, Director of Arquer Diagnostics, said: "As we prepare for EU regulatory submission and market launch of our MCM5-ELISA diagnostic test, we are delighted to be working with the University of Sunderland. The partnership has the potential to extend the application of MCM5-ELISA for use in a wider range of cancers, to benefit both patients and clinicians.”
Arquer recently announced ethical approval for the largest privately funded bladder cancer study in the UK and achieved a key commercial milestone with the announcement of the Companies first manufacturing and supply agreement in February this year.
Photo: Arquer’s MCM5-ELISA test
About Arquer Diagnostics Ltd
Arquer Diagnostics (Arquer) is a private, UK based diagnostics company focused on the development and commercialisation of a non-invasive immunoassay diagnostic test for bladder and prostate cancer. Arquer’s diagnostic test, the MCM5-ELISA, detects the presence of minichromosome maintenance (MCM) protein, a marker for the presence of dividing cancer cells, in urine. MCM proteins are excellent biomarkers, being directly involved in cell replication, and are shed into urine by both prostate and bladder tumours. Arquer’s test is based on intellectual property licensed exclusively from Cancer Research Technology (CRT), the development and commercialisation arm of Cancer Research UK. The non-invasive, urine-based ELISA and Point-of Care tests being developed by Arquer meet the increased demand for cost-effective healthcare technologies that not only enhance patient care but help to reduce overall healthcare costs by improving patient outcomes. The MCM5-ELISA is expected to significantly reduce the number of patients undergoing invasive and costly techniques such as cystoscopy and biopsy, because it offers highly accurate diagnostic results from small amounts of body fluid.
For more information, please visit http://www.arquerdx.com/
Immunoassay - ELISA
Immunoassays are quick and accurate tests to detect specific molecules. Immunoassays rely on an antibody to bind to the specific structure of a molecule. Antibodies are proteins generated by animals in response to the invasion of a foreign molecule (anti...
Benign Prostatic Hyperplasia (BPH) Erectile Dysfunction Urology Urology is the branch of medicine concerned with the urinary tract and diseases that affect it. Examples include urethritis, urethrostenosis and incontinence. Urology is a su...
Cancer is not just one disease but many diseases. There are more than 100 different types of cancer. Most cancers are named for the organ or type of cell in which they start - for example, cancer that begins in the colon is called colon cancer; cancer th...