Novartis to Develop Cerulean Nanoparticle-Drug Conjugates in Cancer Collaboration

06:55 EDT 19 Oct 2016 | Genetic Engineering News

Novartis will partner with Cerulean Pharma to develop nanoparticle-drug conjugates (NDCs) that combine Cerulean’s proprietary Dynamic Tumor Targeting™ technology with Novartis’ proprietary compounds, to be directed at up to five undisclosed cancer targets. Cerulean said today it will generate $5 million upfront through the companies’ collaboration, plus funding for five full-time equivalent employees. Cerulean may potentially make millions more in payments tied to achieving preclinical, clinical, regulatory, and sales milestones for each target. Following regulatory approvals, Cerulean could also earn single-digit to low double-digit tiered royalties on net sales for each NDC product. Under the collaboration, Cerulean will create NDC candidates using its Dynamic Tumor Targeting platform, with Novartis agreeing to oversee further development and commercialization of those products. “This collaboration is further validation of our powerful technology platform, and we are excited that Novartis is including NDCs in its drug discovery and development efforts,” Cerulean ...

Original Article: Novartis to Develop Cerulean Nanoparticle-Drug Conjugates in Cancer Collaboration


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