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Variants of the PCSK9 and HMGCR genes linked to lower LDL were associated with protection from CV events and increased risk for diabetes in certain populations, according to findings published in The New England Journal of Medicine. The researchers compared the effects of lower LDL levels conferred by the variants of PCSK9 and HMGCR on risk for CV events and diabetes. They wrote that PCSK9 variants mimic the effects of PCSK9 inhibitors, and the HMGCR variants mimic the effects of statins.
Original Article: Two genetic variants may reduce CV event risk, increase diabetes riskNEXT ARTICLE
Diabetes is a lifelong condition that causes a person's blood sugar level to become too high. The two main types of diabetes are: type 1 diabetes type 2 diabetes In the UK, diabetes affects approximately 2.9 million people. There are a...