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Scientists find possible Achilles heel of treatment-resistant cancers

20:00 EDT 19 Mar 2017 | AAAS

(Cincinnati Children's Hospital Medical Center) Scientists identify two signaling proteins in cancer cells that make them resistant to chemotherapy, and show that blocking the proteins along with chemotherapy eliminate human leukemia in mouse models. Reporting results March 20 in Nature Medicine, researchers at Cincinnati Children's Hospital Medical Center suggest that blocking the signaling proteins c-Fos and Dusp1 as part of combination therapy might cure several types of kinase-driven, treatment-resistant leukemia and solid tumor cancers.

Original Article: Scientists find possible Achilles heel of treatment-resistant cancers

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