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Complement in ANCA-associated vasculitis: mechanisms and implications for management

14:02 EDT 20 Mar 2017 | Nature Publishing

Accumulating evidence indicates that activation of the complement system is crucial for the development of anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV). This Review provides an overview of the role of complement activation in AAV, and discusses how targeting this pathway can provide opportunities for treatment.

Original Article: Complement in ANCA-associated vasculitis: mechanisms and implications for management

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