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Heptares, PeptiDream Partner on GPCR-Targeting Drugs for Inflammatory Diseases

04:22 EDT 29 Jun 2017 | Genetic Engineering News

Heptares Therapeutics and PeptiDream established a strategic collaboration to discover, develop and commercialize therapeutics targeting a jointly selected, undisclosed G protein-coupled receptor (GPCR) implicated in inflammatory diseases. No financial details have been disclosed. U.K.-based Heptares, which is a wholly owned subsidiary of Japan’s Sosei Group, will apply its StaR® platform to generate 3D target structure information. Japanese firm PeptiDream will use its proprietary Peptide Discovery Platform System (PDPS) to identify macrocyclic/constrained peptides against the GPCR target, and to optimize peptides and/or small molecules for further development. The partners will combine their respective expertise and resources to advance candidates into the clinic, and jointly conduct and share the costs of discovery and development. Any resulting products will also be co-owned. Malcolm Weir, CEO at Heptares and chief R&D officer at Sosei, said, "In bringing together Heptares and PeptiDream technologies under this collaboration, we hope to create a ...

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