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Transcriptional Activation via CRISPR-dCas9 Mimics Overexpression Phenotypes in Arabidopsis

13:00 EDT 2 Aug 2017 | ISAAA

The CRISPR-Cas9 system allows effective gene modification through RNA-guided DNA targeting. Researchers have significantly altered Cas9, resulting in partially or completely deactivated Cas9. The deactivated Cas9 (dCas9) offers a platform to regulate transcriptional expression with the addition of an activator or repressor.The team of Jong-Jin Park...

Original Article: Transcriptional Activation via CRISPR-dCas9 Mimics Overexpression Phenotypes in Arabidopsis

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Bioinformatics is the application of computer software and hardware to the management of biological data to create useful information. Computers are used to gather, store, analyze and integrate biological and genetic information which can then be applied...