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11 Organizations Urge Caution, Not Ban, on CRISPR Germline Genome Editing

06:20 EDT 4 Aug 2017 | Genetic Engineering News

One day after publication of a landmark study detailing the first-in-the-U.S. use of CRISPR to repair a germline mutation in human embryos created through in vitro fertilization, 11 genetics-focused professional organizations are calling for researchers to use caution in applying the technology. The 11 organizations have issued a policy statement stopping short of calling for a ban on human germline genome editing. But the groups added that future clinical application of the technology should not proceed without at least a “compelling” medical rationale, a base of evidence that justifies clinical use, an ethical justification, and the solicitation and incorporation of stakeholder input through a “transparent public process.” “Currently, there is no reason to prohibit in vitro germline genome editing on human embryos and gametes, with appropriate oversight and consent from donors, to facilitate research on the possible future clinical applications of gene editing,” the organizations declared. The ...

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Bioinformatics is the application of computer software and hardware to the management of biological data to create useful information. Computers are used to gather, store, analyze and integrate biological and genetic information which can then be applied...