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Clues about immune resolution identified in blood

06:06 EDT 4 Aug 2017 | Medical Xpress

Stopping a wound from bleeding is essential for human health. Blood coagulation - in which blood goes from liquid to gel and forms a clot - can prevent excessive bleeding and infection. But exactly what molecular events transpire when blood coagulates has remained somewhat mysterious. Using a new profiling procedure invented by investigators from Brigham and Women's Hospital permitted them to elucidate the role of immunoresolvents - molecules that help resolve inflammation and infections -in blood coagulation, identifying a new cluster of these molecules that are produced when blood coagulates. The team's findings are published online in Science Signaling.

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