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Uromodulin: from physiology to rare and complex kidney disorders

04:59 EDT 7 Aug 2017 | Nature Publishing

Uromodulin is the most abundant urinary protein. Here, the authors discuss the physiological roles of uromodulin, the mechanisms by which mutations in the UMOD gene, which encodes uromodulin, cause autosomal dominant tubulointerstitial kidney disease and the association of common UMOD variants with complex disorders in the general population.

Original Article: Uromodulin: from physiology to rare and complex kidney disorders

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