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Prostate cancer cells become 'shapeshifters' to spread to distant organs

20:00 EDT 7 Aug 2017 | AAAS

(Johns Hopkins Medicine) Johns Hopkins Kimmel Cancer Center scientists report they have discovered a biochemical process that gives prostate cancer cells the almost unnatural ability to change their shape, squeeze into other organs and take root in other parts of the body. The scientists say their cell culture and mouse studies of the process, which involves a cancer-related protein called AIM1, suggest potential ways to intercept or reverse the ability of cancers to metastasize, or spread.

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