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Fooling the Heart to Be Healthier

06:42 EDT 8 Aug 2017 | Genetic Engineering News

They say that hope deferred makes the heart sick. Well, those that have suffered heart attacks just got some good news that may afford them some new optimism and lead toward improved cardiac health. A team of investigators from The Ottawa Hospital, the University of Ottawa, the University of Ottawa Heart Institute, and Carleton University have discovered that a protein called cardiotrophin 1 (CT1) can trick the heart into growing in a healthy way and pumping more blood, just as it does in response to exercise and pregnancy. Findings from the new study—published online today in Cell Research in an article entitled “ Cardiotrophin 1 Stimulates Beneficial Myogenic and Vascular Remodeling of the Heart ”— shows that this kind of heart growth is very different from the harmful enlargement of the heart that occurs during heart failure. "When part of the heart dies, the remaining muscles try to ...

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