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Celgene Ends Option to Buy Sutro, Gains Rights to I/O Candidates in Revised Collaboration

05:39 EDT 10 Aug 2017 | Genetic Engineering News

Celgene has ended its option to acquire Sutro Biopharma in return for gaining full global rights to a second Sutro preclinical program, and outside-U.S. rights to two others, in a reworking of the companies’ immuno-oncology collaboration whose value was not disclosed. A revised agreement allows Celgene to acquire worldwide rights to the second Sutro preclinical program to reach investigational new drug (IND) status, in return for unspecified payments to Sutro—while retaining such rights to the first preclinical program that advances to an IND, as called for under a 2014 expansion of the collaboration. That first preclinical program is an antibody drug conjugate (ADC) program designed to fight multiple myeloma by targeting B-Cell maturation antigen (BCMA), a program disclosed earlier by Celgene. The other three preclinical programs are intended to develop immuno-oncology bispecific monoclonal antibodies against undisclosed targets. Celgene also secured ex-U.S. rights to the next two ...

Original Article: Celgene Ends Option to Buy Sutro, Gains Rights to I/O Candidates in Revised Collaboration

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