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Does a Common Food Preservative Trigger Obesity?

07:13 EDT 11 Aug 2017 | Genetic Engineering News

Is it possible that fetal exposure to chemicals contained in everyday household objects such as carpets, paints, or cookware could be responsible for causing obesity in children and adults? It’s a question that scientists have been asking for a number of years, and mounting evidence in animal models—as well as a few epidemiological studies—suggests that some types of environmental chemicals, known as endocrine disrupting chemicals (EDCs), can affect the body’s hormonal control of hunger and satiety, interfere with normal homeostatic control mechanisms, and possibly cause obesity. Researchers at the Cedars-Sinai Board of Governors Regenerative Medicine have now developed a human induced pluripotent stem cell (iPSC)-derived cell platform as a model to show that a number of these EDCs do disrupt normal signaling between the developing digestive system and brain to trigger how we feel "full" after eating. The studies, led by Dhruv Sareen, Ph.D., assistant professor of biomedical ...

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