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The emerging complexity of the tRNA world: mammalian tRNAs beyond protein synthesis

13:27 EDT 6 Sep 2017 | Nature Publishing

tRNAs exist as diverse species, including sequence isoforms and nuclease-generated fragments, which are further functionally diversified by base modifications and various protein interactions. Perhaps unsurprisingly, tRNAs are now being implicated in various cellular processes beyond protein synthesis per se, including in stress responses, proliferation, cell fate determination and tumorigenesis.

Original Article: The emerging complexity of the tRNA world: mammalian tRNAs beyond protein synthesis

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