Akt-dependent Skp2 mRNA translation is required for exiting contact inhibition, oncogenesis, and adipogenesis

Akt-dependent Skp2 mRNA translation is required for exiting contact inhibition, oncogenesis, and adipogenesisNogueira et al identify a novel, translational component of AKT to regulate Skp2 level. General significance comes from two distinct biologic..

Original Article: Akt-dependent Skp2 mRNA translation is required for exiting contact inhibition, oncogenesis, and adipogenesis

 Channels 50 Associated Channels

• Contact Lenses

• Contact Ulcers

• Contact Dermatitis

• Angiotensin inhibition

• Irritant contact dermatitis ICD

• Allergic contact dermatitis ACD

• Rigid Corneal Contact Lenses

• Soft Hydrophilic Contact Lenses

• Polo like kinase Plk 1

  Polo-like kinase (Plk) is an important cell cycle regulatory kinase that has been implicated in a multitude of cell cycle events. Plks form a family of four different proteins that regulates many as...

• Checkpoint kinase 1 CHK 1

  Progression through the cell cycle is monitored by surveillance mechanisms known as cell cycle checkpoints. Dysfunction in cell cycle checkpoints leads to genomic instability and contributes to tumo...

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contact inhibition arrest pyruvate kinase, akt dependent skp2 mRNA translation