Arabidopsis E2FA stimulates proliferation and endocycle separately through RBR-bound and RBR-free complexes
Arabidopsis E2FA stimulates proliferation and endocycle separately through RBR-bound and RBR-free complexesThe transcription factor E2FA stimulates mutually exclusive plant cell-cycle states, mitotic proliferation and differentiation-associated endoc..
Original Article: Arabidopsis E2FA stimulates proliferation and endocycle separately through RBR-bound and RBR-free complexes
Channels 20 Associated Channels 
Proliferation inducing ligand APRIL
Treatment of inflammatory and autoimmune diseases such as systemic lupus erythematosus (SLE), rheumatoid arthritis and multiple sclerosis.
Sphingosine 1 Phosphate S1P
Sphingosine-1-phospate (S1P) is a phospholipid released by platelets, mast and other cells. It is now known that S1P stimulates at least five different G-protein coupled receptors (GPCRs): S1P1, S1P2,...
Sphingosine 1 Phosphate S1P
Sphingosine-1-phospate (S1P) is a phospholipid released by platelets, mast and other cells. It is now known that S1P stimulates at least five different G-protein coupled receptors (GPCRs): S1P1, S1P...
Duchenne muscular dystrophy - DMD
Duchenne muscular dystrophy (DMD) is a severely debilitating childhood neuromuscular disease that affects 1 in 3,500 live male births. This rare disease is caused by mutations in the dystrophin gene...
Hodgkin lymphoma
Hodgkin Lymphoma is a disorder caused by malignant proliferation of lymphocytes, which contain characteristic mirror-image nuclei (Reed-Sternburg cells). The resulting lymphadenopathy can be l...
Serine Threonine protein kinase C PKC
The serine/threonine protein kinase C (PKC) family consists of at least 11 mammalian isozymes belonging to a larger subclass of protein kinases termed the adenine-guanine-cytosine (AGC) kinases. PK...
Interleukin 17 IL 17R IL 17
The IL-17 family consists of six ligands, A-F. IL-17 was originally thought to signal via the classic receptor IL-17R, but IL17 stimulates a receptor complex that consists of the subunits IL-17RA and...
Virulence Factors
Virulence factors are molecules expressed and secreted by pathogens (bacteria, viruses, fungi and protozoa) that enable them to achieve the following: * colonization of a niche in the host (this i...
Allergies
The term allergy is used to describe a response, within the body, to a substance, which is not necessarily harmful in itself, but results in an immune response and a reaction that causes symptoms an...
Hypoxia Inducible Factor HIF
Hypoxia-inducible factor 1 (HIF-1) is a key regulator of angiogenic and glucose metabolism processes utilised by tumour cells for survival and growth under hypoxic conditions. While HIF-1α prote...