November 21, 2002.
The TAXUS programs continue to demonstrate that Boston Scientific’s (NYSE:
BSX) paclitaxel-eluting stent systems will be an important addition to the interventional cardiologist’s armamentarium against clinically significant, blood flow-limiting coronary artery disease including disease that leads to unstable angina, myocardial infarction (MI, heart attack), or sudden cardiac death.
The 1,326-patient, TAXUS IV, 30-day clinical trial data presented at the American Heart Association meetings reinforced the 1,172-patient data generated by Boston Scientific’s Express paclitaxel-eluting stent system reported in the September 30, 2002 BT Report. The additional 154 patients all had longer, more complex lesions. Major adverse cardiac event (MACE) rates remained assuring, and the next longer-term follow-up data are expected “next summer.”
Boston Scientific also updated TAXUS I data. 12-month follow-up in the 61-patient trial of the slow-release paclitaxel formulation showed continued efficacy reassurance as only one target vessel has required revascularization in the paclitaxel-coated stent group, whereas 3 have required revascularization on the bare stent group. Moreover, one coronary artery bypass graft (CABG) has been required in the bare stent group.
The first drug-coated stents, led by Johnson & Johnson’s (NYSE:
JNJ) Cypher system, should hit the U.S. market next year. Even if it is second to market, Boston Scientific’s system should have impressive commercial success.
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