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UK biotechs: biting off more than they can chew

Five non-profitable UK biotech companies may be considering a merger, creating a new cancer player capable of competing against the pharmaceutical majors and of raising the funds needed to create a strong pipeline. But while it seems exciting, the merger could prove a logistical nightmare. A more gradual consolidation effort might suit the biotechs better.

In the 20 years since the UK's biotech industry began, mergers and acquisitions have been rare; founder-managers have been reluctant to let go of the reins. However, several of Britain’s biggest biotechs are now reportedly holding secret talks to forge a major global cancer company.

The initiative is believed to involve cancer specialists Xenova, Antisoma, British Biotech and KS Biomedix, and cash-rich Oxford GlycoSciences. Other possible companies include gene specialist Oxford Biomedica and vaccine firm Protherics, not to mention Vernalis, Alizyme and PPL Therapeutics.

British Biotech is a spin-off from Oxford University, as are proteomics-focused Oxford GlycoSciences and gene therapy firm Oxford Biomedica. The merger of these three companies would bring synergies in efficiencies, economics, logistics and technology. Antisoma makes monoclonal antibodies, while Xenova focuses on small molecules and biologics.

During the last few years, all the mooted partners have experienced a decline in the value of their shares, due principally to key pipeline failures such as the non-approval of OGS’ Vevesca (miglustat) for type I Gaucher’s disease. Most are also suffering from a lack of the cash required to develop a strong pipeline.

But while the drive for funds could make a merger attractive, the resulting company would immediately be competing head-to-head with major players such as AstraZeneca, Novartis, Bristol-Myers-Squibb and Roche. And there has never been a five-company merger in the history of the biotechnology industry; while potentially exciting, it could be a logistical nightmare.

Instead, the partners could form an independent joint venture, feeding from all their technologic and developmental strengths. Alternatively, smaller initial mergers could be followed by further consolidation over a period of five years, in a model similar to that seen at the top end of the pharma industry. Either option would be preferable to a full mega-merger - or to going it alone.

Related research: Datamonitor, "Biotechnology Company Growth Strategies" (DMHC1728)

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Biotechnology Company Growth Strategies: Intra-biotech Collaborations Bring Independence from Pharma One Step Closer
Biotechnology Company Growth Strategies: Intra-biotech Collaborations Bring Independence From Pharma One-Step Closer; analyzes changes in biotechnology company growth strategies. It presents a primary research based analysis of the long-term growth strategies of biotechnology companies and the tactics employed to achieve growth. It draws upon 20 in-depth company case studies to identify the characteristics that define success at each stage of the biotechnology growth curve (fully integrated, developing, co-developing and technology platform companies). Each chapter benchmarks financial performance, details major collaborations, discusses the most successful growth strategies and predicts future growth plans. It also forecasts the impact of eight market factors on the biotechnology market. Each factor is illustrated with reference to three scenarios, that project the impact of a positive, negative or stationary outcome. This provides the framework for strategic recommendations to improve biotechnology company growth prospects in the face of changing biotechnology market conditions, and the impact of this changing environment on the pharmaceutical sector. Report Code: DMHC1728 Report Format: PDF

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Price:   $6,100.00 / £3,904.00

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