DNA Sequencing News: Breaking DNA Sequencing News, Comments and Articles. - Page: 3

Researchers take important step in unlocking what causes congenital heart disease

(NIH/National Heart, Lung and Blood Institute) Findings from the first large-scale sequencing analysis of congenital heart disease bring us closer to understanding this most common type of birth defect.

Sequenom jumps on 1Q13 revenues

Sequenom Inc. (NASDAQ:SGNM) gained $0.47 (13%) to $4.04 on Friday after the company reported 1Q13 revenues of $38.5 million, up 158% over $14.9 million in 1Q12. The Street was expecting $38.3 million. Diagnostics revenues for the quarter were $29 mil...

Molex Subsidiary Polymicro Technologies Showcases Capillary Tubing at 37th International Symposium on Capillary Chromatography

Polymicro capillary tubing designed for scientific, industrial, environmental and medical applications Polymicro Technologies, a subsidiary of Molex Incorporated, will

NEB Releases a New Site-Directed Mutagenesis Kit for Both Standard and Novel Uses, Including Long Insertions and Deletions

IPSWICH, Mass., May 10, 2013 /PRNewswire/ -- New England Biolabs (NEB), a world leader in the discovery and production of reagents for the life science industry, launched a new reagent kit for site-directed mutagenesis (SDM). The Q5® Site-Directed Mutagenesis Kit (Q5 SDM Kit) is capable of introducing long insertions and deletions, thus allowing a broader range of applications for this widely...

State-Of-The-Art DNA Sequencing Technique Reveals Cause Of Severe Childhood Epilepsies

Researchers at the University of Arizona have successfully determined the genetic mutations causing severe epilepsies in seven out of 10 children for whom the cause of the disorder could not be determined clinically or by conventional genetic testing...

A cautionary tale on genome-sequencing diagnostics for rare diseases

(Sanford-Burnham Medical Research Institute) Sanford-Burnham researchers discover that several children born with rare diseases called congenital disorders of glycosylation don't contain the mutation in every cell type -- raising new questions about...

Gribbles Pathology and Sengenics Enter Into Partnership to Deliver Cutting-Edge Genetic Tests

Kuala Lumpur, Malaysia, May 09, 2013 --(PR.com)-- Gribbles Pathology and Sengenics today announced an exclusive partnership to deliver genetic-based clinical tests in Malaysia. The aim of the partnership, between Gribbles, one of Asia and Australasia’s leading private pathology laboratories and Sengenics, a leading genetic diagnostics company is to make cutting-edge tests more accessible t...

Meta-analysis methods for genome-wide association studies and beyond

The authors review statistical methods for meta-analysis of genome-wide association studies (GWASs) and extensions of these methods to complex data. They discuss how low-frequency variants can be incorporated into meta-analyses as next-generation seq...

Good Start Genetics pharma deals for $28 million loan financing

Good Start Genetics has closed a pharma deals non-dilutive loan facility for up to $28 million of financing from Capital Royalty. Good Start Genetics, the specialty pharma company, will use the financing proceeds of pharma deals to support its long-term corporate growth initiatives for the company’s next-generation sequencing based carrier screening platform. Good Start Genetics is [...]The pos...

CollabRx and GeneInsight to collaborate on clinical genetic sequencing reporting service

CollabRx, Inc, a data analytics company focused on informing the clinical interpretation of molecular diagnostic testing, and GeneInsight LLC, a developer of software to support knowledge management and reporting for genetic testing laboratories, hav...

Dendreon Announces First Quarter 2013 Results

Conference Call to be Hosted May 9, 2013 at 9:00 a.m. ET May 9, 2013--Dendreon Corporation (Nasdaq:DNDN) today reported results for the first quarter ended March 31, 2013. Net product revenue for the quarter was $67.6 million compared to $82.0 million for the quarter ended March 31, 2012, down 17.6% year over year. Net loss in the first quarte...

Dendreon: New Trial Sequencing Provenge With Xtandi To Begin Q4

By Theodore Cohen:Earlier this year, I alerted readers to the fact that sequencing Dendreon's (DNDN) Provenge after Medivation's (MDVN) Xtandi produced startling results. Specifically, I am speaking about the paper by Graff, et al., "Complete Biochemical (Prostate-specific Antigen) Response to Sipuleucel-T With Enzalutamide in Castration-resistant Prostate Cancer: A Case Report With Implications f...

Patients should have right to control genomic health information

Doctors should not have the right or responsibility to force-feed their patients with genomic information about their future health risks, according to bioethicists writing on May 9 in Trends in Biotechnology, a Cell Press publication. They write in...

Patients should have right to control genomic health information, experts say

Doctors should not have the right or responsibility to force-feed their patients with genomic information about their future health risks, according to bioethicists. They write in response to controversial recommendations from the American College of...

Family Tree DNA Offers mtDNA Test For $49

HOUSTON, May 9, 2013 /PRNewswire/ -- FamilyTreeDNA.com, the genetic genealogy arm of Gene By Gene, Ltd., has lowered the price of its mid-level maternal line mtDNA test to $49, effective immediately.  The company announced it will offer its mtDNAPlus product at a two-third price reduction permanently, in just its latest step toward universal access by individuals to their personal genetic dat...

WaferGen Launches SmartChip TE - A Novel Target Enrichment Solution for Next-Gen Sequencing (NGS) Aimed at Clinical Applications

FREMONT, Calif., May 9, 2013 /PRNewswire/ -- WaferGen Bio-systems, Inc. (OTCBB: WGBS) today announced the launch of its new SmartChip TE product – a PCR-based target enrichment solution for sample preparation prior to targeted re-sequencing on Next-Gen platforms. As clinical Next-Gen sequencing rapidly expands into the mainstream molecular testing market, the growth of this mar...

Adaptive Biotechnologies Signs Biomarker Discovery Collaboration Agreement with Bristol-Myers Squibb

SEATTLE, May 9, 2013 /PRNewswire/ -- Adaptive Biotechnologies announced today that it has entered into a collaboration agreement with Bristol-Myers Squibb for the discovery of immunological biomarkers in oncology.  (Logo: http://photos.prnewswire.com/prnh/20120103/SF28632LOGO) Under the collaboration, Adaptive will use its proprietary immune profiling assay, immunoSEQ, to identify po...

Predictive Biomarker Discovery for Oncology Small-Molecules and Biologics - a Webinar Hosted by Xtalks

Toronto, Canada (PRWEB) May 09, 2013 Recent advances in next-generation sequencing technologies are revolutionizing the way human disease is defined, providing avenues to develop novel, individualized therapies that target the genomic underpinning...

Immune surveillance by CD8αα+ skin-resident T cells in human herpes virus infection

Most herpes simplex virus 2 (HSV-2) reactivations in humans are subclinical and associated with rapid expansion and containment of virus. Previous studies have shown that CD8+ T cells persist in genital skin and mucosa at the dermal–epidermal jun...

The AAPS Journal: Epigenetic Modifications of Nrf2 by 3,3′-diindolylmethane In Vitro in TRAMP C1 Cell Line and In Vivo TRAMP Prostate Tumors

Type: Original Paper3,3′-diindolylmethane (DIM) is currently being investigated in many clinical trials including prostate, breast, and cervical cancers and has been shown to possess anticancer effects in several in vivo and in vitro models. Previo...

Saving The Parrots: Texas A&M Team Sequences Genome Of Endangered Macaw Birds

COLLEGE STATION, Texas, May 8, 2013 /PRNewswire-USNewswire/ -- In a groundbreaking move that provides new insight into avian evolution, biology and conservation, researchers at Texas A&M University have successfully sequenced the complete genome of a Scarlet macaw for the first time. (Logo: http://photos.prnewswire.com/prnh/20120502/DC99584LOGO) The team was led by Drs. Christopher Seabury...

Game-Changing Discovery of Gene Mutation That Causes Sturge-Weber Syndrome, Port-Wine Stain Birthmarks Offers New Hope

BALTIMORE, Md., May 8, 2013 /PRNewswire-USNewswire/ -- In new findings published today in the New England Journal of Medicine (Epub ahead of print), researchers from the Kennedy Krieger Institute reveal the discovery of the cause – a genetic mutation that occurs before birth – of Sturge-Weber syndrome (SWS) and port-wine stain birthmarks. SWS is a rare disorder affecting approxima...

New England Biolabs Releases the NEBNext Microbiome DNA Enrichment Kit

IPSWICH, Mass., May 8, 2013 /PRNewswire/ -- New England Biolabs (NEB) announces the release of the NEBNext® Microbiome DNA Enrichment Kit, which uses a novel method to separate microbial DNA from host DNA, thereby reducing the high cost of sequencing microbiome DNA to a more practical level. (Logo:  http://photos.prnewswire.com/prnh/20090921/NE79207LOGO-b ) Microbiome samples are...

Research makes advance in nanotech gene sequencing technique

The allure of personalized medicine has made new, more efficient ways of sequencing genes a top research priority. One promising technique involves reading DNA bases using changes in electrical current as they are threaded through a nanoscopic hole.R...

Good Start Genetics Announces $28 Million Financing from Capital Royalty

Good Start Genetics®, Inc., an innovative molecular diagnostics company that has developed the new gold standard in carrier screening, today announced that it has closed a non-dilutive loan facility for up to $28 million of capital from Capital Royalty L.P. Good Start Genetics will use the proceeds to support its long-term corporate growth initiat...