Epigenetic News: Breaking Epigenetic News, Comments and Articles.

Abbott aids Epizyme in matching epigenetic drug with cancer patients

April 18, 2013 - Abbott plans to develop a companion diagnostic test for an experimental leukemia drug from the biotech startup Epizyme.

Early Identification And Treatment Of Postpartum Depression Can Limit Or Prevent Debilitating Effects

The epigenetic modifications, which alter the way genes function without changing the underlying DNA sequence, can apparently be detected in the blood of pregnant women during any trimester, potentially providing a simple way to foretell depression i...

Charles A. Moss, M.D. Announces "The Adaptation Diet"

A Three-Step Approach to Control Cortisol, Lose Weight, and Prevent Chronic Disease Charles A. Moss, M.D., nationally acclaimed pioneer of integrative medicine, lecturer and author, announces the release of his new book, The Adaptation Diet: A Three-Step Approach to Control Cortisol, Lose Weight, and Prevent Chronic Disease. Based on 35 years of...

Epigenetic Regulators And NF-Kappa B May One Day Be Targeted For The Treatment Of Cancer

In a new study described in the journal Oncogene, researchers reveal how a key player in cell growth, immunity and the inflammatory response can be transformed into a primary contributor to tumor growth. Scientists call this Jekyll-and-Hyde molecule...

Researchers Link Two Genes To Postpartum Depression

Lee Rannals for redOrbit.com – Your Universe Online Researchers writing in the journal Molecular Psychiatry say they found an alteration of two genes that may foretell whether someone will experience postpartum depression. The Johns Hopkins Medicine team studied 52 pregnant women to determine what factors to consider when attempting to predict whether someone will experience postpartum depres...

Physicians and Nurses to Learn Meditation and Yoga at The American Meditation Institute’s Fifth Annual CME course on Mind/Body Medicine

The American Meditation Institute (AMI), in joint sponsorship with the Albany Medical College, will present the fifth annual mind/body medicine CME course on meditation and yoga for physicians, nurses and other health care professionals, November 6-10, 2013 at the Cranwell Resort and Spa in Lenox, Massachusetts. Averill Park, NY (PRWEB) May 21, 2013 The American Meditation Institute (AMI), in joi...

Stronger epigenetic changes in estrogen responsive genes linked to postpartum depression

The epigenetic modifications, which alter the way genes function without changing the underlying DNA sequence, can apparently be detected in the blood of pregnant women during any trimester, potentially providing a simple way to foretell depression i...

Researchers Identify Genetic Predictors of Postpartum Depression

Johns Hopkins researchers say they have discovered specific chemical alterations in two genes that, when present during pregnancy, reliably predict whether a woman will develop postpartum depression. The epigenetic modifications, which alter the way genes function without changing the underlying DNA sequence, can apparently be detected in the blood of pregnant women during any trimester, potent...

Ignyta Announces Acquisition of Actagene Oncology and Entry into Oncology Personalized Medicine

--Company adds world class drug discovery and development veterans to management and advisory team-- Ignyta, Inc. announced today that it has acquired Actagene Oncology, Inc., effective May 20, 2013. Actagene was a San Diego based privately held biotechnology company founded in February 2013 that was developing personalized medicines for high unmet nee...

Selexis SA to Present Technology Platform Data at Cell Line Development & Engineering

Selexis’ co-founder and scientific advisory board member will present, “Engineering the CHO Genome for Improved Transgene Integration and Expression” Geneva, Switzerland (PRWEB) May 20, 2013 Selexis SA, a serial innovation company focused on drug discovery for lead identification and cell line development for scale-up and manufacturing of therapeutic protein drugs, announced today that the...

Acetylon Pharmaceuticals to Present at UBS Global Healthcare Conference

Acetylon Pharmaceuticals Inc., the leader in targeted epigenetic drug discovery and development for enhanced therapeutic outcomes, today announced that Walter C. Ogier, President and Chief Executive Officer of Acetylon, will present at the UBS Global Healthcare Conference today, May 20, 2013, at 1:00 p.m. ET in New York City in the Riverside South room at...

The plasticity and stability of regulatory T cells

In this Viewpoint article, several experts share their thoughts on the plasticity and stability of regulatory T cells, discussing the recent advances in our understanding of the transcriptional and epigenetic regulation of this important T cell subse...

NDRI Awarded $5.9M by NIH for Genotype-Tissue (GTEx) Project Scale Up

The National Disease Research Interchange (NDRI) has been awarded $5,955,435 by the National Institutes of Health (NIH) for the next phase of human tissue collection for the Genotype-Tissue Expression (GTEx) project—an NIH initiative begun

Origins and implications of pluripotent stem cell variability and heterogeneity

Pluripotent stem cell lines differ in their capacity to differentiate into desired cell types in vitro. Genetic and epigenetic variations contribute to functional variability between cell lines and heterogeneity within single clones. Characterizing s...

Epigenetics of embryonic stem cells

Epigenetic modifications play a major role in cell differentiation, helping to determine which genes are transcribed in divergent cell lines. But it is difficult to observe the DNA of individual cells of an embryo during development. A paper publishe...

Epigenetics: BPA and imprinting disruption

Epigenetics: Genome-wide views of methylation readers

Syndax Pharmaceuticals Announces Publication of Clinical Study Demonstrating that Entinostat Targets Resistance Pathways in Breast Cancer

WALTHAM, Mass., May 14, 2013 /PRNewswire/ -- Syndax Pharmaceuticals, Inc., a late-stage oncology company focused on developing novel combination epigenetic strategies to treat cancers that have become resistant to standard treatments, announced today the publication in the Journal of Clinical Oncology of positive results of a phase 2 randomized, double-blind, placebo-controlled study of the c...

Cardiomyopathies and epigenetic inheritance

Epigenetic mechanisms, along with gene mutations, have been shown to play important roles in the development of heart diseases. Researchers from Heidelberg have discovered that the methylation of two specific genes has an impact on the development of dilated cardiomyopathy. These epigenetic modifications have the potential to be used as molecular markers and improve the diagnosis and therapy of th...

Epigenome: Control chart of stem cells that mimic early human development

Scientists know that control mechanisms known collectively as "epigenetics" play a critical role in human development, but not how alterations in this extra layer of biochemical instructions in DNA contribute to development. In the first comprehensi...

NEB Releases a New Site-Directed Mutagenesis Kit for Both Standard and Novel Uses, Including Long Insertions and Deletions

IPSWICH, Mass., May 10, 2013 /PRNewswire/ -- New England Biolabs (NEB), a world leader in the discovery and production of reagents for the life science industry, launched a new reagent kit for site-directed mutagenesis (SDM). The Q5® Site-Directed Mutagenesis Kit (Q5 SDM Kit) is capable of introducing long insertions and deletions, thus allowing a broader range of applications for this widely...

Salk Researchers Find Stem Cell Epigenetic Markers

e Science News | Salk Institute of Biological Sciences finds epigenetic markers influence stem cells in human development. By studying various epigenetic influences, researchers examined the beginning states of cells before they differentiated.

Modifications in key epigenetic markers influence human embryonic stem cells

Scientists have long known that control mechanisms known collectively as "epigenetics" play a critical role in human development, but they did not know precisely how alterations in this extra layer of biochemical instructions in DNA contribute to dev...

Epigenetics: Legionella makes its mark on histones

Epigenetic Regulation of IL-8 and β-Defensin Genes in Human Keratinocytes in Response to Malassezia furfur