Epigenetic News: Breaking Epigenetic News, Comments and Articles. - Page: 2

Genetic Material From 'Dark Genome' Is Involved In Rett Syndrome

Researchers at the Epigenetics and Cancer Biology Program at IDIBELL led by Manel Esteller, ICREA researcher and professor of genetics at the University of Barcelona, have described alterations in noncoding long chain RNA sequences (lncRNA) in Rett s...

New mechanism that plays important role in meiosis identified

The Research Group headed by molecular biologist Andrea Pichler from the Max Planck Institute of Immunobiology and Epigenetics in Freiburg has made an important discovery in meiosis research.

Researchers describe alterations in long noncoding RNA sequences in Rett syndrome

Researchers at the Epigenetics and Cancer Biology Program at IDIBELL led by Manel Esteller, ICREA researcher and professor of genetics at the University of Barcelona, have described alterations in noncoding long chain RNA sequences in Rett syndrome.

New mechanism discovered in meiosis

(Max-Planck-Gesellschaft) The research group headed by molecular biologist Andrea Pichler from the Max Planck Institute of Immunobiology and Epigenetics in Freiburg has made an important discovery in meiosis research. Pichler and her group have ident...

New Application from BMG LABTECH

A Fluorescence Based Assay of the Epigenetic Enzyme Histonedeacetylase 1 (HDAC1)Histone modifications caused by histone deacetylases (HDACs) are strongly related to epigenetic regulation of transcription. Determining the activity of recombinant HDAC1 using the POLARstar OPTIMA microplate reader from BMG LABTECH offers high precision and performance. Using Boc-Lys(Ac)-AMC as fluorescent substr...

Belfer Institute and Evotec establish collaboration in oncology

The Belfer Institute for Applied Cancer Science at Dana-Farber Cancer Institute and Evotec AG (EVT) announced a research collaboration aimed at discovering and commercialising novel cancer treatments based on epigenetic drug mechanisms. The goal of t...

Polymerase IV occupancy at RNA-directed DNA methylation sites requires SHH1

DNA methylation is an epigenetic modification that has critical roles in gene silencing, development and genome integrity. In Arabidopsis, DNA methylation is established by DOMAINS REARRANGED METHYLTRANSFERASE 2 (DRM2) and targeted by 24-nucleotide s...

'Dark genome' is involved in Rett Syndrome

(IDIBELL-Bellvitge Biomedical Research Institute) Researchers at the Epigenetics and Cancer Biology Program at IDIBELL led by Manel Esteller, ICREA researcher and professor of genetics at the University of Barcelona, have described alterations in non...

Resverlogix's Board Approves Arrangement to Spin-Out RVX Therapeutics Inc. and Confirms Special Meeting of Shareholders

TSX Exchange Symbol: RVX CALGARY, May 1, 2013 /PRNewswire/ - Resverlogix Corp. (TSX:RVX) ("Resverlogix") today announced that its Board of Directors has unanimously approved the previously announced Plan of Arrangement ("the Arrangement") to spin-out its subsidiary RVX Therapeutics Inc. ("RVX Therapeutics"). Resverlogix has entered into an Arrangement Agreement with RVX Therapeutics and 17...

Dana-Farber's Belfer Institute for Applied Cancer Science, Evotec sign oncology research deal

The Belfer Institute for Applied Cancer Science at Dana-Farber Cancer Institute and Evotec have established a research collaboration to discover new cancer therapies targeting epigenetic mechanisms.

Evotec, Dana-Farber Partner on Cancer Epigenetics Drug Development

Celgene, Forma in protein homeostasis deal

Celgene Corp. (NASDAQ:CELG) partnered with Forma Therapeutics Holdings LLC (Watertown, Mass.) to discover, develop and commercialize compounds that regulate protein homeostasis for multiple disease areas with an emphasis on cancer. Forma will receive...

Autism mechanism goes beyond genes

A study on identical twins with distinct autistic traits suggests that epigenetic factors may be important in understanding how the neurological disorder develops...

FORMA Therapeutics and Celgene Corporation Establish Broad Strategic Collaboration to Advance Innovative Drugs Targeting Protein Homeostasis

FORMA Therapeutics Holdings, LLC (FORMA) today announced a strategic collaboration agreement with Celgene Corporation under which FORMA and Celgene will discover, develop and commercialize drug candidates to regulate protein homeostasis targets. Protein homeostasis, which is important in oncology, neurodegenerative and other disorders, involves a...

All you ever wanted to know about Glyphosate, Biosemiotic Entropy, Disorder, Disease, and Mortality but were too afraid to ask.

Reuters have recently highlighted an article about the herbicide glyphosate from a special issue of an online journal entirely devoted to disorder (Entropy).The text of the surprising Reuters post is here:Heavy use of herbicide Roundup linked to health dangers-U.S. study By Carey GillamApril 25 (Reuters) - Heavy use of the world's most popular herbicide, Roundup, could be linked to a range of...

Epizyme, Inc. Files Registration Statement for Proposed Initial Public Offering

CAMBRIDGE, Mass., April 26, 2013 /PRNewswire/ -- Epizyme, Inc., today announced that it has filed a registration statement on Form S-1 with the U.S. Securities and Exchange Commission ("SEC") relating to the proposed initial public offering of its common stock.  The number of shares to be offered and the price range for the offering have not been determined. Citigroup, Cowen and Company, LLC...

[Epizyme] jumps on board; becomes the fourth biotech to file for a US IPO in April

Cancer epigenetics company [Epizyme Inc.] has filed for its initial public offering. The company is the fourth biotech this month to file for an IPO, behind anticoagulant developer [Portola Pharmaceuticals Inc.], plasma-derived therapeutics company [...

What The Heck Does "Epigenetic" Mean, Anyway?

A lot of people (and I'm one of them) have been throwing the word "epigenetic" around a lot. But what does it actually mean - or what is it supposed to mean? That's the subject of a despairing piece from Mark Ptashne of Sloan-Kettering in a recent PN...

The Role Of Epigenetic Influences In Autism

Scientists from King's College London have identified patterns of epigenetic changes involved in autism spectrum disorder (ASD) by studying genetically identical twins who differ in autism traits. The study, published in Molecular Psychiatry, is the...

The Epigenetics Of Pain In Endometriosis

Most of us probably know at least one woman, and maybe quite a few more, with endometriosis. Despite the disease's prevalence, there is no consensus on the cause of it, the existing treatment options leave a lot to be desired, and there are too few w...

Pain, epigenetics and endometriosis

BOSTON — Most of us probably know at least one woman, and maybe quite a few more, with endometriosis. Despite the disease's prevalence, there is no consensus on the cause of it, the existing treatment options leave a lot to be desired, and there ar...

Pain, epigenetics and endometriosis: Research team wants to know how molecular tweaks affect which women hurt the most

Most of us probably know at least one woman, and maybe quite a few more, with endometriosis. Despite the disease's prevalence, there is no consensus on the cause of it, the existing treatment options leave a lot to be desired, and there are too few w...

Grandma's Experiences Leave a Mark on Your Genes

Your ancestors' lousy childhoods or excellent adventures might change your personality, bequeathing anxiety or resilience by altering the epigenetic expressions of genes in the brain.

Epigenetic changes shed light on biological mechanism of autism

(King's College London) Scientists from King's College London have identified patterns of epigenetic changes involved in autism spectrum disorder (ASD) by studying genetically identical twins who differ in autism traits. The study, published in Molec...

NEB Releases CutSmart™ Buffer and Sets New Standard for Restriction Enzyme Convenience and Performance

IPSWICH, Mass., April 22, 2013 /PRNewswire/ -- New England Biolabs (NEB), a leader in the production of reagents for the life science industry, announces the release of CutSmart Buffer. This latest development from NEB supports an industry-leading portfolio of over 200 restriction enzymes that exhibit 100% activity in a single buffer. With CutSmart Buffer, it is significantly easier to s...