Latest Biotechnology, Pharmaceutical and Healthcare News

01:12 EDT 29th September 2016 | BioPortfolio

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Thursday 29th September 2016

[Personal View] Elimination of visceral leishmaniasis on the Indian subcontinent

Visceral leishmaniasis is a serious public health problem on the Indian subcontinent, causing high morbidity and mortality. The governments in the region launched a visceral leishmaniasis elimination initiative in 2005. We review knowledge gaps and research priorities. Key challenges include low coverage of health services for those most at risk, drug resistance, the absence of a vaccine, and the ...

Wednesday 28th September 2016

[Articles] Interventions to prevent and reduce physician burnout: a systematic review and meta-analysis

The literature indicates that both individual-focused and structural or organisational strategies can result in clinically meaningful reductions in burnout among physicians. Further research is needed to establish which interventions are most effective in specific populations, as well as how individual and organisational solutions might be combined to deliver even greater improvements in physician...

[Comment] Doing something about physician burnout

Burnout affects more than half of practising physicians and is on the rise.1 When burnout was seen as a crisis of wellbeing—affecting physicians' personal lives and work satisfaction—it garnered little public sympathy and could be dismissed as the whining of a privileged class. Now that evidence suggests that burnout negatively affects physicians' effectiveness and availability to patients, as...

Huanzhong Biotech to Market Concepta's Fertility Product in China

Shijiazhuang Huanzhong Biotech (HZ Biotech) will assemble and market a new women's fertility product in China developed by Concepta of the UK. The My Lotus product consists of test strips and electronic meters that measure a woman's cyclic urinic hormone levels, identifying the most likely time for conception. HZ Biotech will purchase the product from Concepta, market it, and provide post-market s...

ReedCoor Raises $23 Million from China Investors for Novel NGS Technology

ReadCoor, a next generation sequencing spin-out from Harvard University, has closed an oversubscribed $23 million Series A financing from China-affiliated healthcare investors. The round was led by Decheng Capital and joined by Lilly Asia Ventures, Vivo Capital and Hansjörg Wyss. ReedCoor will commercialize an innovative FISSEQ (fluorescent in situ sequencing) technology that combines sequenc...

[Articles] and genetic modifiers of age of onset in LRRK2 Gly2019Ser parkinsonism: a genome-wide linkage and association study

Genetic variability in DNM3 modifies age of onset for LRRK2 Gly2019Ser parkinsonism and informs disease-relevant translational neuroscience. Our results could be useful in genetic counselling for carriers of this mutation and in clinical trial design.

[Comment] Modifiers of LRRK2 parkinsonism: new therapeutic targets

The number of genetic susceptibility loci for Parkinson's disease—once believed to be the archetypal non-genetic disorder—has been growing with each genome-wide association study.1 Although a total of 26 independent risk loci have been reported, mutations in leucine-rich repeat kinase 2 (LRRK2) are the most common cause of familial Parkinson's disease, and several LRRK2 risk variants have been...

New tool for recognizing physician distress, preventing suicide

  Physicians die by their own hands at much higher rates than do members of the general public—40 percent higher in males and 130 percent higher in females—so recognizing and responding to physician distress is crucial. Physicians themselves are uniquely positioned to do this for their colleagues, but many are uncomfortable intervening and unsure what steps to take if they do get involved...

Takeda Obtains New Drug Application Approval for Inisync® Combination Tablets for the Treatment of Type 2 Diabetes in Japan

Osaka, Japan, September 28, 2016 – Takeda Pharmaceutical Company Limited (TSE: 4502) today announced that Takeda has obtained the New Drug Application Approval from the Ministry of Health, Labour and Welfare for the Inisync® Combination Tablets, a fixed-dose combination of Nesina® (gen

5 tips to start and grow a happy family during residency

Residency often coincides with the time when many young physicians would like to start families, but undertaking these two life events simultaneously can be daunting. A third-year family medicine resident with three young children recently shared her tips for making it work with minimal stress. When Chelsea Slade, MD, and her husband began talking about having kids, she was in medical school a...

New Gene Study Highlights the Helpfulness of Medical Weight Loss Support, says Beverly Hills Physicians

Commenting on a recent article, the Los Angeles-based health and beauty clinic notes that genetics is only part of the equation in dealing with weight loss and obesity issues. Los Angeles, CA (PRWEB) September 28, 2016 As reported in a September 21 article on Medical News Today, a new international study indicates that people with a genetic predisposition to obesity are able to lose weight at rou...

Congress approves $1.1 billion in Zika funding

The Zika funding will go toward vaccine research and health care in the hard-hit southern states, such as Florida, as well as Puerto Rico.

Senate approves $1.1 billion in Zika funding

The Zika funding will go toward vaccine research and health care in the hard-hit southern states, such as Florida, as well as Puerto Rico.

Human mini-guts: new insights into intestinal physiology and host–pathogen interactions

The development of indefinitely propagating human 'mini-guts' has led to a rapid advance in gastrointestinal research. This Review highlights the uses of enteroids, colonoids and organoids in functional transport physiology studies and host–pathogen studies.

Therapeutic intervention in oropharyngeal dysphagia

This Review describes the current state of the evidence related to therapies for oropharyngeal dysphagia — focusing on treatments most clinically utilized and of current interest to researchers.

Liver cancer: IGF2 — an epigenetic oncodriver in HCC

FDA Grants Roche Label Extension for the cobas® EGFR Mutation Test v2 for use with Plasma as a Companion Diagnostic for TAGRISSO™

PLEASANTON, Calif., Sept. 29, 2016 /PRNewswire/ -- Roche (SIX: RO, ROG; OTCQX, RHHBY) today announced that the U.S. Food and Drug Administration (FDA) has approved a label extension of the cobas® EGFR Mutation Test v2 for use with plasma samples as a companion diagnostic for Astra Zeneca's non-small cell lung cancer (NSCLC) therapy TAGRISSO™ (osimertinib). "The label extension for the ...

Apricus Biosciences Closes $3.7 Million Registered Direct Offering

SAN DIEGO, Sept. 28, 2016 (GLOBE NEWSWIRE) -- Apricus Biosciences, Inc. (Nasdaq:APRI), a biopharmaceutical company advancing innovative medicines in urology and rheumatology, today announced that it has closed a registered direct offering of shares of common stock with institutional investors for gross proceeds of approximately $3.7 million.  Based on feedback from the Nasdaq stock market, ...

Updated & Expanded Commentary - Prepping for Prothena's Immiment Announcements on PRX003

For the past few weeks, we have maintained that Prothena was going to update its plans regarding PRX003 in September 2016. Prothena announced that it will host a conference call on Thursday, September 29, 2016.  This article should prep you for the upcoming announcement and call.When: 4:30pm (ET), Thursday, September 29, 2016How: Conference Call Webcast         (877) ...

Intra-Cellular Shares Sink As Schizophrenia Drug Flunks Final Test

Several promising antipsychotic drugs have made it to late-stage clinical trials only to come up short. Today, you can add an experimental treatment from Intra-Cellular Therapies to the list. Shares of New York-based Intra-Cellular (NASDAQ: [[ticker;ITCI]]) cratered late Wednesday, falling more than 67 percent in after-hours trading after the company disclosed that its experimental schizophrenia [...

The global scourge of counterfeit medicines

Pharmaceuticals are a prime target for organised crime

Bio Execs Talk Patient Advocacy, Duchenne Approval at BioForward Panel

 Janet Woodcock, the top drug evaluator at the FDA, was the driving force behind the FDA’s recent decision to approve eteplirsen (Exondys 51), a drug for patients with Duchenne muscular dystrophy from Cambridge, MA-based Sarepta Pharmaceuticals (NASDAQ: SRPT). The decision was controversial: Many FDA scientists didn’t want to approve eteplirsen. They didn’t want to lower […]

Take Action This World Heart Day

GENEVA, September 29, 2016 /PRNewswire/ -- This World Heart Day (29 September 2016), the World Heart Federation (WHF) is urging people around the globe to use the power of information to transform the 1 in 10 lives that are being cut short prematurely as a direct result of cardiovascular disease (CVD).[1]      (Logo: ) CV...

ARIAD Announces Regulatory Approval for Iclusig® (ponatinib) in Japan

Wednesday, September 28th 2016 at 11:35am UTC Approval triggers $10 million milestone payment to ARIAD CAMBRIDGE, Mass.–(BUSINESS WIRE)– ARIAD Pharmaceuticals, Inc. (NASDAQ: ARIA) today announced that its partner Otsuka Pharmaceutical Co., Ltd. (Otsuka) has received approval from the Japanese Pharmaceuticals and Medical Devices Agency (PMDA) for Iclusig® (ponatinib) for the treatment ...

Catabasis Pharmaceuticals Announces Closing of $11.5 Million Offering of Common Stock, Including Full Exercise of Underwriter’s Option to Purchase Additional Shares

Wednesday, September 28th 2016 at 8:15pm UTC CAMBRIDGE, Mass.–(BUSINESS WIRE)– Catabasis Pharmaceuticals, Inc. (NASDAQ: CATB), a clinical-stage pharmaceutical company, today announced the closing of an underwritten offering of 2,875,000 shares of its common stock, including 375,000 shares purchased by the underwriter pursuant to the exercise in full of its option to purchase additional...

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