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Inpharmatica Announces Biopendium Online [TM] Subscription Agreement with Taisho of Japan

Third Japanese subscriber to proteome annotation resource
 
London, UK,  March 29, 2004 -- Inpharmatica Ltd, announced today that it has signed a non-exclusive Biopendium Online [TM] subscription with Taisho Pharmaceuticals Co., Ltd.
 
Biopendium Online [TM], launched last year, allows subscribers to access Biopendium through a secure internet connection. Taisho is the third Japanese Biopendium subscriber, and the first to use the online version.
 
Researchers at Taisho will be using Biopendium Online [TM] in their drug discovery efforts.  Biopendium [TM] will give them immediate access to high quality annotation for all the 1.4 million sequences available from 150 different genomes in Biopendium [TM]'s database.  Biopendium [TM] generates a wealth of annotation information not available elsewhere, including 3D structure and ligand data.  This means it is a valuable aid across a range of popular research problems such as: microarray annotation, target prioritisation and cloning.  Taisho, and all other subscribers, will also benefit having further improvements in protein annotation provided to them with each new quarterly Biopendium [TM] release.
 
Biopendium [TM] is the advanced annotation component of PharmaCarta [TM], Inpharmatica's knowledge-based chemogenomics platform.

Commenting on the announcement, Dr Vimal Mehta, Senior Vice President of Business Development at Inpharmatica, said:
"We are delighted to be announcing Taisho as our third Biopendium [TM] subscriber in Japan.  We are sure that Taisho will find Biopendium Online [TM] invaluable in assisting them with their mission to create superior pharmaceuticals.  The fact that we are continuing to add subscribers to our database highlights the need for this information within the global pharmaceutical industry.  We are fully committed to ensuring that we provide an industry leading resource to all our customers and consequently will to be making significant enhancements to this technology in 2004."
 
Notes to Editors
About Inpharmatica (www.inpharmatica.com)
Inpharmatica Ltd is a selective drug discovery company that is applying its expertise in structural and computational biology, and medicinal chemistry to the identification of quality drug targets, chemical leads and drug candidates, thereby reducing attrition in the drug discovery process.  The Company's lead discovery program is focused upon the development of 16 novel Nuclear Receptors ("NR's"), a family of proteins widely considered to be both druggable and of high therapeutic interest.  Drugs targeted against NR's generate more than $10bn in sales annually.  Inpharmatica's novel NR's represent a more than a 30% increase on those identified in the public domain.
 
The Company's technology platform, PharmaCarta [TM], is applied internally and available to collaborative partners.  It's a flexible and integrated chemogenomics suite that links genomic and proteomic space with chemistry, and provides a unique approach to hit identification, lead generation and drug optimisation for druggable targets.  This platform utilises the massive computing power of the Company's 2,500- processor compute farm, one of the largest in the world. Biopendium [TM] and ADME services, both integral parts of PharmaCarta [TM] are also available stand-alone. The Company has sales and collaboration partnerships with leading biotech and pharma companies including Serono, Pfizer, Daiichi, Riken, Aventis, UCB Pharma, Galapagos and Genentech.
 
Founded in 1998, Inpharmatica's technology is based on research from Professor Janet Thornton's group at University College London.  The Company employs some 100 staff at its UK locations  London and on the Cambridge Science Park. To date the Company has raised some £34.6m from leading venture capitalists including Unibio, 3i, GIMV, Dresdner Kleinwort Capital, Advent Venture Partners, Abingworth Mgt, Gilde Investment, Vertex Mgt and Genentech Inc.

About Taisho ( http://www.taisho.co.jp
  )
Taisho ranks highest in Japan in OTC drugs.  At present, it is aiming to strengthen its position in the field of prescription pharmaceuticals and is actively expanding its cooperation with companies both inside and outside Japan.
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