OTC-Drugs News: Breaking OTC-Drugs News, Comments and Articles. - Page: 4

[Comment] P-glycoprotein expression and antiepileptic drug resistance

One of the most frustrating aspects of treating people with epilepsy is the inability to predict who will respond to antiepileptic drugs and who will be treatment resistant. Many theories of treatment resistance have been proposed, including associat...

Mannitol could prevent aggregation of toxic proteins in the brain, says Tel Aviv University researcher

Mannitol, a sugar alcohol produced by fungi, bacteria, and algae, is a common component of sugar-free gum and candy. The sweetener is also used in the medical field - it's approved by the FDA as a diuretic to flush out excess fluids and used during s...

Pyrvinium pamoate inhibits drug-resistant prostate cancer

A new drug called pyrvinium pamoate inhibits aggressive forms of prostate cancer that are resistant to standard drugs, according to a study conducted in an animal model. The results will be presented Monday at The Endocrine Society's 95th Annual Meet...

AMA Adopts New Policies on Second Day of Voting at Annual Meeting

CHICAGO, IL--(Marketwired - June 18, 2013) -  The American Medical Association (AMA), the nation's largest physician organization, voted today during its Annual Meeting to adopt the following new policies on emerging issues in public health and science: OPPOSITION TO GENETIC DISCRIMINATIONThe AMA today adopted policy strongly opposing discrimination based on an individual's genetic information....

Variant Of Main Painkiller Receptor Designed

Opioids, such as morphine, are still the most effective class of painkillers, but they come with unwanted side effects and can also be addictive and deadly at high doses. Designing new pain-killing drugs of this type involves testing them on their co...

Partnership Aims to Take Advantage of Preclinical Ophthalmology Developments

Calvert Labs and EyeCRO have teamed up, citing growing demand for integrated early-phase services for ocular drugs.

SMC approves linaclotide but rejects ivacaftor again

The Scottish Medicines Consortium has approved linaclotide for restricted NHS use in Scotland, but rejected ivacaftor and fluocinolone acetonide intravitreal implants. The SMC’s June assessments mean patients with irritable bowel syndrome can n...

EMA restricts use of diclofenac

Patients who have serious underlying heart or circulatory conditions should not use systemic diclofenac, the European Medicines Agency has concluded. Furthermore, patients with certain cardiovascular risk factors (such as high blood pressure, raised...

Setback for Pacts That Delay Sale of Generics

The U.S. Supreme Court ruled that courts should give more scrutiny to pharmaceutical industry patent settlements that can delay the entry of generic drugs.

Testing Asthma Drugs on a Microchip

Forget lab rats. Some researchers are now testing medicines on a silicon chip that could provide a better read on how a drug will work.

An article in 'Cell' reveals a new resistance mechanism to chemotherapy in breast and ovarian cancer

(Centro Nacional de Investigaciones Oncologicas (CNIO)) The team led by Spanish National Cancer Research Centre researcher Óscar Fernández-Capetillo, head of the Genomic Instability Group, together with researchers from the National Cancer Institut...

Pioneering breakthrough of chemical nanoengineering to design drugs controlled by light

(Institute for Research in Biomedicine (IRB Barcelona)) Researchers at IRB Barcelona and IBEC achieve photo-switchable molecules to control protein-protein interactions in a remote and non-invasive manner.These tools will serve as a prototype to deve...

Study shows how the Nanog protein promotes growth of head and neck cancer

(Ohio State University Medical Center) Researchers have identified a biochemical pathway in cancer stem cells that is essential for promoting head and neck cancer. The study shows that a protein called Nanog, which is normally active in embryonic ste...

Research shows moves to ban pay-to-delay deals are justified

(University of East Anglia) Controversial deals that delay generic versions of drugs coming onto the market can lead to consumers paying significantly more for some treatments, according to new research by an academic from the University of East Angl...

UPDATE 2-J&J in $1 bln deal to bolster prostate-cancer focus

By Ransdell Pierson June 17 (Reuters) - Johnson & Johnson said it would pay up to $1 billion for Aragon Pharmaceuticals and its experimental drugs for prostate cancer, to bolster J&J's role in the field after it acquired another experimental prostate...

Purdue Pharma L.P. To Present Data Describing Changes in Oxycodone Abuse in Rural Kentucky Following the Introduction of Reformulated OxyContin® (Oxycodone HCl Controlled-Release) at the College on Problems of Drug Dependence 2013 Annual Meeting

SAN DIEGO, June 17, 2013 /PRNewswire/ -- Purdue Pharma L.P. will present a poster describing the changes in abuse of OxyContin® and immediate-release oxycodone in rural Kentucky following the August 2010 introduction of reformulated OxyContin. This data is composed of follow-up interviews with a cohort of individuals in Kentucky who self-identified as original OxyContin abusers...

WHO Issues Interim Guidance on the Use of Bedaquiline to Treat MDR-TB

The World Health Organization (WHO) estimates that up to half a million new cases of multidrug-resistant tuberculosis (MDR-TB) occur worldwide, each year. Current treatment regimens for MDR-TB present many challenges: treatment lasts 20 months or more, requiring daily administration of drugs that are more toxic, less effective, and far more

India Drug Regulator To Encourage Whistleblowers, Add To Port Testing

India's Central Drugs Standard Control Organization plans to bolster its policy for encouraging whistleblowers in the pharmaceutical industry to disclose information about "spurious drugs," according to an official.

Statins plus certain antibiotics may set off toxic reaction, study says

(HealthDay)—Doctors should avoid ordering certain antibiotics for older patients who take cholesterol-lowering statin drugs, such as Lipitor, Canadian researchers say.

Drug Settlements Can Face Antitrust Scrutiny

The U.S. Supreme Court ruled that courts should give more scrutiny to pharmaceutical industry patent settlements that can delay the entry of generic drugs.

Conatus Pharmaceuticals Files for $69M IPO to Advance Liver Drugs

San Diego’s Conatus Pharmaceuticals, founded in 2005 and developing new drugs to treat chronic liver disease, plans to raise as much as $69 million through an IPO, according to a regulatory filing unsealed Friday. The biotech plans to take advantag...

BioScrip Buying Drug Infusion Company for $223M

BioScrip Inc. plans to expand its drug infusion business with a $223 million acquisition of CarePoint, which administers drugs to patients in their homes and other locations outside of hospitals. BioScrip, of Elmsford, N.Y., provides medication infus...

J&J in $1 billion deal to bolster prostate-cancer focus

By Ransdell Pierson (Reuters) - Johnson & Johnson said it would pay up to $1 billion for Aragon Pharmaceuticals and its experimental drugs for prostate cancer, to bolster J&J's role in the field after it acquired another experimental prostate-cancer...

IQWiG again rebuffs Caprelsa

Germany's Institute for Quality and Efficiency in Healthcare (IQWiG) said thyroid cancer drug Caprelsa vandetanib from AstraZeneca plc (LSE:AZN; NYSE:AZN) provides "no additional benefit" over best supportive care, the comparator requested by Germany...

Co-Development Guidance Gives More Attention To IND, NDA/BLA Submissions

In a final guidance on co-development of two or more investigational new drugs for use in combination, FDA lays out general principles for IND and marketing application submissions, a topic on which the agency essentially punted in a December 2010 dr...