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15:14 EDT 29th May 2016 | BioPortfolio

Calorics Pharmaceuticals

Calorics Pharmaceuticals, is leveraging novel insight into the biology of dietary restriction and nutrient sensing to discover and develop novel drugs to improve human healthspan. Investors include Polaris Partners, Atlas Venture and Johnson & Johnson Development Corp.

SeLux Diagnostics

What do North Korea’s porn habits say about their culture?

John Hopton for redOrbit.com - @Johnfinitum A new video from PornHub, one of the leading porn sites in the world, gives an insight into pornography use in North Korea. Based on their own stats, PornHub enlightens us as to the habits of North Koreans in terms of demographic, time per visit and fetishes. What can this tell us about North Korea’s secretive culture? First off, here’s the video (...

Euro-American Connections, LLC Establishes Comprehensive Independent Homecare Program in Response to New FLSA Overtime Regulations

Euro-American Connections & Homecare is the premier homecare provider in Connecticut specializing in Eastern-European caregivers. Berlin, Conn. (PRWEB) October 23, 2015 Euro-American Connections & Homecare (EACH) – the premier homecare provider in Connecticut specializing in Eastern-European caregivers – through its referral registry, Euro-American Connections, LLC (EAC), has develope...

Benylin Four Flu Liquid discontinued

Johnson & Johnson has discontinued Benylin Four Flu Liquid 20ml (paracetamol, diphenhydramine hydrochloride, pseudoephedrine hydrochloride).

Ipsen Inks Radiopharmaceutical Licensing Deal With 3B Pharmaceuticals

Ipsen says it will focus on developing the lead program currently in preclinical development for treating pancreatic adenocarcinoma and possibly other indications too. The German company will be eligible to receive development and regulatory milestone...

McKesson laying off 1,600 employees

The company had previously warned of weaker performance this year. 

AstraZeneca präsentiert positive Tagrisso (Osimertinib) Follow-up-Daten zu Lungenkrebs auf der ELCC 2016

Phase-I-Erstlinien-Tagrisso-Daten belegen eine objektive Ansprechrate von 77% und ein progressionsfreies Überleben von 19,3 Monaten bei Patienten mit EGFRm NSCLC 1 Die aktualisierten Ergebnisse fü...

Lemtrada shows clinical efficacy in multiple sclerosis in 10-year follow-up data

Sanofi Genzyme has presented 10-year follow-up data on Lemtrada (alemtuzumab) which points to its efficacy in patients with relapsing-remitting multiple sclerosis (RRMS). The ongoing Phase II CAMMS223 study showed that, over 10 years of follow-up, 76% of patients were shown to be free from 6-month confirmed disability worsening. Furthermore, a low annualised relapse rate (ARR) was maintained (0.0...

OBÉSITÉ: Stabiliser sa perte de poids, c'est possible! - European Journal of Endocrinology

Le maintien d'une perte de poids puis d'un poids stable est l'objectif ultime mais difficile pour les personnes obèses. Cette étude de l'Université de Copenhague apporte de nouvelles connaissances sur les processus complexes impliqués dans l'obésité. Avec des implications pratiques, elle permet de mieux communiquer aux patients en surpoids la meilleure fa&...

The Bell Agency and Indiana Non-Profit ‘Art With A Heart’ Launch Joint Charity Initiative for At-Risk Children in Marion County

The Bell Agency, a full service insurance firm that serves families and businesses in Indianapolis region, is joining Marion County non-profit organization “Art With A Heart” in a cooperative charity drive to benefit at-risk youth in surrounding communities Indianapolis, IN (PRWEB) April 26, 2016 The Bell Agency, a Marion County insurance firm with offices serving communities in and around th...

ULCÈRE du PIED DIABÉTIQUE: Pourquoi l'attitude du patient est déterminante - PLOS ONE

Cette recherche de psychologues de l'Université de Nottingham montre l'impact des croyances et les attentes des patients souffrant d'ulcères du pied diabétique sur leur cicatrisation voire leur survie. L'étude, publiée dans la revue PLoS ONE, confirme les résultats de précédentes études, soit l'impact négatif de la dépres...

VIEILLISSEMENT: Ces enzymes clés capables de prolonger la durée de vie - Cell

A nouveau au cœur de cette étude sur la longévité et la durée de vie en bonne santé, ces mini-usines à énergie cellulaire, les mitochondries (Visuel ci-contre). Cette étude de l'Université de Californie Berkeley décrypte comment le stress mitochondrial et de brefs changements dans l'énergie disponible pour la cellul...

Widely Used Heart Drug Tied to Dementia Risk

THURSDAY, May 5, 2016 -- People with the heart rhythm disorder atrial fibrillation may have a heightened risk of developing dementia -- and the quality of their drug treatment may play a role, a new study hints. Specifically, researchers found,...

NICE Recommends Praluent, Repatha for Treating Cholesterol

NICE has published final draft guidance recommending 2 new treatment options for some people who have conditions that put them at extremely high risk of heart attacks or strokes.Read more about NICE Recommends Praluent, Repatha for Treating CholesterolComments

FDA Decision On Eteplirsen: Disappointing But A Big Step Forward

A recent FDA advisory committee hearing on the Duchenne muscular dystrophy drug eteplirsen resulted in a recommendation against approval. Pat Furlong of the advocacy group Parent Project Muscular Dystrophy was disappointed in the decision, but also sees it as a big step forward for patients and caregivers.

Baxalta sues Chugai for haemophilia drug patent breach

Baxalta has taken Chugai Pharmaceuticals to the Tokyo district court, claiming that the Japanese company has infringed upon its patent rights with their new haemophilia drug candidate, emicizumab (ACE910). Emicizumab is currently in late stage trials for the treatment of haemophilia A. The study, co-sponsored by Roche, has set the number of bleeds over time to be the primary endpoint of the trial,...

ME is more than just tiredness – the truth about chronic fatigue syndrome | BT.com Lifestyle | 12 May 2016

From BT.com Lifestyle, 12 May 2016. Words by Susan Griffin. People have long approached sufferers of myalgic encephalopathy (ME) with suspicion. Those living with ME – also known as chronic...

Proton Pump Inhibitors Accelerate Cellular Aging

A new study suggests that chronic use of a proton pump inhibitor (PPI) accelerates aging of endothelial cells. Reuters Health Information

Last Month in Oncology with Bishal Gyawali: April 2016

ecancer blogger Dr Bishal Gyawali rounds up the latest publications in oncology.   PCV in Glioma: not an industry-sponsored trial It is very rare that you see the primary trial result published in JCO, but the long-term follow up results of the...

Ladas Super Formula aims to improve refractive accuracy of cataract surgery

We have all seen it in our own patients: After a seemingly routine cataract surgery that is without complications, the patient ends up with a refractive miss. Even though we were aiming for a plano refraction, the patient is a diopter away from that. For a patient electing for cataract surgery alone, this is still a successful case because the patient was not electing for vision correction. But fo...

Animal health firm Genus to fund gene editing programme

Animal genetics specialist Genus PLC (LON:GNS) is to collaborate with gene editing technology firm Caribou Biosciences. The multi-year strategic collaboration will see Genus received an exclusive global licence for Caribou's CRISPR-Cas0 gene editing platform for use on certain livestock species. Caribou's CRISPR-Cas9 technology accurately targets and cuts DNA to produce precise and controllabl...

Forget the sci-fi horror stories. Here’s what we could really learn from a synthetic genome

Building genomes from scratch could yield new insights into human disease.

Why does cancer affect men and women differently?

The GLP aggregated and excerpted this blog/article to reflect the diversity of news, opinion and analysis. Researchers are shedding new light on why cancer is often a different disease for men than it is for women. A new study suggests that for many cancers, important differences in the genetics of tumors in men as compared […] The post Why does cancer affect men and women differently? app...

Glide begins solid dose, injectable acromegaly drug trial on birthday of most famous sufferer

A solid dose version of the acromegaly treatment octreotide developed by Glide Technologies has entered a proof-of-concept study.

FDA updates Nutrition Facts Panel

Michael JohnsenThe FDA is also making minor changes to the Supplement Facts label found on dietary supplements to make it consistent with the Nutrition Facts label. read more

Pharma Consulting Firm Expands European Presence Via UK Office

Pennside Partners, a pharmaceutical and biotechnology consulting firm, announced the opening of their UK office in Alderly Edge, south of Manchester. Located in the BioHub at Alderly Park, the new location will enable the firm to expand their delivery of services throughout the EU. Alderly Edge, United Kingdom (PRWEB) May 23, 2016 As a result of expanding business and a desire to better serve its...

French study’s death recalls 2006 UK clinical trial disaster

It was an unsettling sense of deja vu for researchers and bioethicists when French authorities reported in January that one man died and five others were seriously injured after being administered an investigational drug in a Phase I clinical trial.

Vitamin D: Study Finds Impaired Fertility

(MedPage Today) -- Study highlights potential adverse effects of too much vitamin D

50 varslas på AstraZeneca

50 personer kommer att få lämna sina tjänster vid bolagets sajt i Södertälje som en del av ett besparingsprogram.

Aberrant PD-L1 expression through 3′-UTR disruption in multiple cancers

Successful treatment of many patients with advanced cancer using antibodies against programmed cell death 1 (PD-1; also known as PDCD1) and its ligand (PD-L1; also known as CD274) has highlighted the critical importance of PD-1/PD-L1-mediated immune escape in cancer development. However, the genetic basis for the immune escape has not been fully elucidated, with the exception of elevated PD-L1 exp...

Gilead Brings Back Kevin Young, Former Commercial Exec, As New COO

Gilead Sciences (NASDAQ: GILD) has brought back former top executive Kevin Young as chief operating officer. Young spent the past two years as an advisor to the Foster City, CA-based drug maker, and before that was its EVP of commercial operations for ten years. Young’s return fills a gap left by Paul Carter, who replaced […]

Bayer-Aktie: Was Analysten zur Monsanto-Offerte sagen, was BÖRSE ONLINE empfiehlt

Der deutsche Pharma- und Chemiekonzern Bayer hat mit einem Übernahmeangebot für den umstrittenen US-Saatguthersteller Monsanto seine Anleger vergrault. Doch ist die Angst berechtigt? BÖRSE ONLINE h...

BRIEF-Novavax says FDA has granted fast track designation for its RSV F-protein vaccine

* Says U.S. FDA has granted fast track designation for its RSV F-protein nanoparticle vaccine candidate Source text for Eikon: Further company coverage: (Bengaluru Newsroom: +1-646-223-8780)

DIAXONHIT and the University Hospitals of Strasbourg launch the Central European Laboratory dedicated to AlloMap® testing

DIAXONHIT - Heart transplant monitoring DIAXONHIT and the University Hospitals of Strasbourg launch the Central European Laboratory dedicated to AlloMap® testing AlloMap®, the new molecular test to monitor heart transplant patients Paris & Strasbourg, France - May 25, 2016 - DIAXONHIT (Alternext: ALEHT, FR0004054427), the leading French provider of specialty in-vitro diag...

Pitx2 promotes heart repair by activating the antioxidant response after cardiac injury

Myocardial infarction results in compromised myocardial function and heart failure owing to insufficient cardiomyocyte self-renewal. Unlike many vertebrates, mammalian hearts have only a transient neonatal renewal capacity. Reactivating primitive reparative ability in the mature mammalian heart requires knowledge of the mechanisms that promote early heart repair. By testing an established Hippo-de...

Valeant rejected joint takeover bid from Takeda, TPG in spring-WSJ

May 26 (Reuters) - Valeant Pharmaceuticals International Inc received a joint takeover offer from Japan's Takeda Pharmaceutical Co Ltd and TPG Capital Management LP this spring that the Canadian drugmaker rejected, the Wall Street Journal reported,...

Generic Injectables

LONDON, May 26, 2016 /PRNewswire/ -- The generic injectable drug segment is a rapidly evolving and highly competitive market that lacks a true data compass to assist decision makers in mapping strategies for success in this segment. Attempting to determine the optimal time to file an ANDA application is a process that can be worth significant profits for first-to-filers. But it is a process that i...

BRIEF-U.S. FDA approves Zinbryta to treat multiple sclerosis

* Zinbryta has a boxed warning & is available only through a restricted distribution program under a risk evaluation and mitigation strategy

Iowa Becomes Fourth State to Allow Psychologists to Prescribe Medications

WASHINGTON, May 27, 2016 /PRNewswire-USNewswire/ -- The American Psychological Association hailed the enactment today of a law making Iowa the fourth state in the country to authorize licensed clinical psychologists with advanced specialized training to prescribe certain medications for the treatment of mental health disorders. "This is a landmark decision that will improve access to a wide ...

VerioMed Launches Data Driven Healthcare Platform for Labs and Hospitals, to Dramatically Improve Revenues

Los Angeles, CA, May 28, 2016 --(PR.com)-- VerioMed, developer of innovative healthcare cloud software, announced the launch of its next generation data driven healthcare platform for clinical labs and hospitals across United States, to generate and save millions of dollars in revenues. Available as a cloud ready product, VerioMed platform includes CRM, Intelligence, Analytics and Order Entry mo...

The bittersweet truth about the epidemic affecting health care workers

It was the first day of my prestigious internship at the cardiac and pulmonary rehabilitation center. I was a senior in college and eager to apply my knowledge from the field of exercise physiology to make an impact on the people beginning rehab. This was my first real opportunity to work as part of a […]

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