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15:53 EST 14th February 2016 | BioPortfolio

Zika virus infection – Maldives

On 7 January 2016, the National IHR Focal Point of Maldives notified WHO of a case of Zika virus infection with onset of symptoms in June 2015, in a patient returning to Finland. The patient is a 37-year-old Finnish male who returned to Finland on 16 June 2015 after spending several months in the Maldives. On 18 June, the patient developed symptoms (mild fever and rash on the face and trunk, as w...

Two GPs face charges of manslaughter over death of boy in 2012

Two GPs have appeared in court charged with the manslaughter by gross negligence of a 12 year old patient who died in December 2012 in Wales.Joanne Rudling, 45, and Lindsey Thomas, 42, entered not...

The Significant Unmet Need in Chronic Lymphocytic Leukemia (CLL)

A paradigm shift in the treatment of chronic lymphocytic leukemia (CLL) has taken place over the past decade, as therapies have progressed from providing palliative relief to inducing complete remission, eradicating minimal disease, and improving survival. The development of rituxan (rituximab) and its use in immunochemotherapy regimens has transformed the treatment of CLL and is […] The pos...

FDA approves Consentyx from Novartis

Ryan ChavisThe Food and Drug Administration on Wednesday announced approval for Cosentyx (secukinumab), indicated for the treatment of adults with moderate to severe plaque psoriasis.   read more

Average penis is 5.16 inches long, study says

Chuck Bednar for redOrbit.com - @BednarChuck Since the dawn of time, the question has been in the back of every male member of the species’ mind: how does the size of my penis compare to everyone else? Now science has finally given us the answer, in the form of a new study published Tuesday in the journal BJU International. In the study, Dr. David Veale, of King's College London and his collea...

Inflamax Research announces the opening of its US Phase 1 to 3 Clinical Research Site in Neptune, New Jersey

This 45,000 sq. ft, 150 bed state-of-the-art Phase 1 Unit has been at the same site for over 10 years and has conducted over 200 Phase 1 and 2 studies in healthy volunteers and disease specific populations. Toronto, Ontario (PRWEB) May 21, 2015 Inflamax Research, Inc., today announces the acquisition and opening of a clinical research site in Neptune, New Jersey. The site, which was acquired from...

USP <1207> Updates Leak Testing Recommendations for Pharmaceutical Companies

Package integrity is defined as a package’s ability to prevent product loss, maintain product sterility, and in some cases, prevent oxygen ingress or maintain sub-atmosphere headspace pressures. As a result, container closure integrity testing is an important step in the preparation and transportation of many different products. Unlike other mass produced devices, blood filters, catheters, d...

JDSU MicroNIR spectrometer

The MicroNIR spectrometer is an ultracompact, lightweight near-infrared (NIR) spectrometer that combines JDSU’s high-volume, high-precision optical coating technology with innovation in optical system design and miniaturisation. The spectrometer relies on the company’s linear variable filter (LVF) technology as the dispersing element. The spectrometer contains a light source, collection optic...

Orthopedic Surgeon, Ryan Palmer, DO to Join OrthoNeuro in August 2015

Columbus, OH, July 06, 2015 --(PR.com)-- OrthoNeuro announced today that Dr. Ryan Palmer will join their multi-specialty physician practice August 10th, 2015. Dr. Palmer is a fellowship-trained orthopedic surgeon who specializes in adult total joint reconstruction. He will offer a full spectrum of hip and knee replacement surgery, from primary replacement to complex revision. For total hip arthr...

Disease Interception – Predict & Pre-Empt

Only when people feel unwell do they start to look for the causes of their disease; traditionally, pharmaceutical companies have been there to provide the medication and treatments necessary. However, Janssen Research & Development, LLC (Janssen), a Johnson and Johnson (J&J) company, has a progressive new approach to disease, aimed at earlier intervention to prevent disease progression. In...

Parent–progeny sequencing indicates higher mutation rates in heterozygotes

Mutation rates vary within genomes, but the causes of this remain unclear. As many prior inferences rely on methods that assume an absence of selection, potentially leading to artefactual results, we call mutation events directly using a parent–offspring sequencing strategy focusing on Arabidopsis and using rice and honey bee for replication. Here we show that mutation rates are higher in hetero...

New Paradigm Biosciences

New Paradigm Biosciences is a biotech company dedicated to developing therapies using humanized mouse models and other cutting edge technologies. The Company has exclusive licenses to technologies developed at MIT, University of North Carolina and Singapore-MIT Alliance for Research and Technology. It has operations in both US and Asia.

U.S. FDA Approves Minerva Endometrial Ablation System

92% of Clinical Study Patients had Their Heavy Menstrual Bleeding Reduced to a Normal Level or Less. Redwood City, CA (PRWEB) August 31, 2015 There’s a new treatment option for excessive menstrual bleeding – The Minerva Endometrial Ablation System. Minerva is the first commercially available new FDA approved system in the last 14 years, and the only endometrial ablation product to combine t...

Newly discovered protein may protect kidney cells from injury

(Boston University Medical Center) A new discovery by Boston University School of Medicine (BUSM) researchers may change how kidney disease is treated in the future.The previously unknown protein transmembrane and immunoglobulin containing 1 (TMIGD1) involved in protecting kidney epithelial cells (cells critical to normal kidney function) from injury, could be a novel target for restoring kidney f...

Is 50 Really the New 30? Your Immune System May Not Think So

Actor Tim Daly in partnership with the American Lung Association and Pfizer launches the WHO PNEU?™ Campaign – Urging adults 50 and older to know their Pneumococcal pneumonia risk The American Lung Association in partnership with Pfizer announces the launch of WHO PNEU?™, a public awareness campaign encouraging Baby Boomers and older Gen X-ers to...

ABPI's Stephen Whitehead steps down

Leaves the UK pharma trade body after four years as its CEO

GenVisc 850 Approved by the FDA for Treatment of Osteoarthritis Knee Pain – Disruptive medical device reducing healthcare cost

OrthogenRx Inc. has announced the US Food and Drug Administration (FDA) approval of GenVisc 850® (sodium hyaluronate) for the treatment of patients with osteoarthritis (OA) knee pain. GenVisc 850® is a solution of purified hyaluronic acid (sodium hyaluronate; HA), similar to the normal knee fluid. HAs replace the fluid in the knee that has degrade...

Teleflex Focuses on Advancing Respiratory Care at AARC Congress 2015

Teleflex Incorporated (NYSE: TFX), a leading global provider of medical technologies for critical care and surgery, will showcase its broad portfolio of products for Respiratory Care at the American Association for Respiratory Care (AARC) Congress 2015, November 7-10, in Tampa, FL. The portfolio includes products for High Flow Nasal Cannula Therapy and Mec...

PD-1 Inhibitor Screening Assay Kit

AMSBIO has announced a new PD-1 (Programmed Death) inhibitor screening assay kit for cancer research studies. Immunotherapy for the treatment of cancer is rapidly evolving from therapies that globally and non-specifically simulate the immune system to more targeted activation of individual components of the immune system. The net result of this targeted approach is decreased toxicity and incr...

Cancer: Organ-seeking vesicles

An analysis reveals that cancer cells remotely prepare distant sites for tumour spread in an organ-specific manner, by deploying organ-seeking extracellular vesicles.

Alexion Snags 2nd FDA Voucher on Kanuma Win

But with the approval, the FDA also issued Alexion a rare pediatric disease priority review voucher (PRV) – making the firm the only company in the US to win two of the so-called golden tickets.

IBM eröffnet Watson-Zentrale in München: IBM will München zur Hauptstadt des Internet der Dinge machen. ...

IBM will München zur Hauptstadt des Internet der Dinge machen. Im Norden der Stadt entsteht eine spezialisierte Zentrale des Supercomputers Watson. Insgesamt sollen hier bis zu 1000 Mitarbeiter bes...

Two studies reveal new ideas on plant form, function and competitive nature

(Phys.org)—Two large international teams of researchers have conducted two separate analysis of the nature of plants and each has found something new. Both teams have had their work published in the latest issue of the journal Nature—the first looks at trait commonalities among plant forms that allow for surviving natural selection. The second looks at the traits that are responsible for givin...

Top Biotech Picks For 2016

GORE BIO-A Tissue Reinforcement Proven as Effective as a Biologic Mesh for Complex Ventral Hernia Repair

Final study results of bioabsorbable mesh shows significant improvement in patient quality of life while offering cost-savings to hospitals and payors W. L. Gore & Associates, Inc. (Gore) today announced final results of a long-term, prospective, multicenter study evaluating the use of GORE® BIO-A® Tissue Reinforcement, a bioabsorbable me...

Study finds West Africa at highest risk of bat-to-human virus spread

LONDON, Jan 5 (Reuters) - Sub-Saharan Africa and South East Asia are most at risk from bat viruses jumping to humans and causing new diseases that could lead to deadly outbreaks, scientists warned on Tuesday.

Teva launches generic Ortho Tri-Cyclen Lo for birth control

Michael JohnsenTeva's new product, Tri-Lo-Sprintec, is indicated for use by females of reproductive potential to prevent pregnancy.  read more

What's Behind Brazil's Alarming Surge in Babies Born with Small Heads

Zika typically causes flulike aches and rash, but the rapidly spreading disease is fueling global worries about tiny-headed infants and brain damage -- Read more on ScientificAmerican.com

Aleta Biotherapeutics

Aleta Biotherapeutics is an immuno-oncology company founded to transform cellular therapeutics to allow a broad spectrum of tumor types to be targeted, including currently intractable solid tumors. Co-founders Paul Rennert and Roy Lobb bring extensive scientific and leadership experience in immunology, oncology and drug development to this new enterprise.

SOIN des PLAIES: Freiner l'inflammation pour accélérer la cicatrisation - International Journal of Inflammation

Ces chercheurs du département de chirurgie plastique de l'Université de São Paulo nous proposent un examen de la littérature sur la première phase nécessaire au processus de cicatrisation des plaies, la réduction ou le contrôle de l'inflammation. Réduire le processus inflammatoire lié à la cicatrisation permet en effet d'a...

How about the $100M Holy ‘GRAIL’ in Cancer Diagnostics? A Universal Test Start-up Faces German Competition

Illumina (the €22Bn Market cap NGS specialist) and Bill Gates pool a $100M for to fund the start-up, ‘Grail’, which will be used to find a universal cancer detection test for Doctors. The start-up will be based in San Francisco ... This awesome article How about the $100M Holy ‘GRAIL’ in Cancer Diagnostics? A Universal Test Start-up Faces German Competition appeared first...

Eltrapuldencel-T: Phase III discontinued

Introducing the Garmin Approach S20: The Golfing Partner That Doubles as an Everyday Watch

Garmin International Inc., a unit of Garmin Ltd. (NASDAQ: GRMN), today announced the Approach S20 GPS golf watch. Stylish, sleek and lightweight, this versatile watch comes preloaded with more than 40,000 courses around the world, plus daily activity tracking and connected features like smart notifications and automatic updates. The new AutoShot feature re...

ChartaCloud Announces Agreement to Offer Skejul for Advanced AI Based Appointment Scheduling in Health Care and Field Services

Portsmouth, NH, January 30, 2016 --(PR.com)-- ChartaCloud Technologies LLC (“ChartaCloud”) today announced that it will introduce the advanced artificial intelligence (AI) appointment scheduling service called Skejul. Skejul has been created to significantly improve the efficiency and effectiveness of setting appointments or meeting dates involving multiple parties. The company stated...

New Specialty Registry for Meaningful Use

The MedXpress Specialty Registry has been appointed by the American Podiatric Medical Association and the American College of Foot and Ankle Pediatrics as a Specialty Registry for Meaningful Use Oceanside, NY (PRWEB) February 03, 2016 The MedXpress Specialty Registry has been appointed by the American Podiatric Medical Association and the American College of Foot and Ankle Pediatrics as a Special...

ANNUAL RESULTS 2015: END-OF-YEAR CASH POSITION OF €60M AND MAJOR PROGRESS IN THE DIAGNOSIS AND THE TREATMENT OF NASH

Cash horizon to early 2017 Phase IIb clinical results for Elafibranor in NASH led to the launch of a Phase III study in the same therapeutic indication Discovery of a diagnostic tool that could replace the liver biopsy for the identification of NASH patients to be treated Lille (France), Cambridge (Massachusetts, United States), February 4th, 2016 - GENFIT (Euronext: GNFT - ...

Biosimilars in UK gain NICE recommendation

Biosimilars may be set to increase their market share in the UK after the country’s healthcare cost watchdog recommended that rheumatoid arthritis patients indicated for treatment with biologicals should ‘start treatment with the least expensive drug’.

AstraZeneca to invest £330 Million in new strategic R&D centre and global headquarters in Cambridge

AstraZeneca today announced its intention to establish a new global R&D centre and corporate headquarters in Cambridge in the UK by 2016. The planned investment of around £330 million ($500 million) to establish a purpose-built site reinforces AstraZeneca’s long-term commitment to the UK and underscores the country’s global importance as a location for biopharmaceutical ...

[Comment] Detection of a novel Lyme borreliosis pathogen

Ticks are vectors of many pathogens of human beings, wildlife, and livestock. Several tick-borne pathogens pose serious threats to public and animal health and cause substantial economic loss.1 Lyme borreliosis, the most common tick-borne disease in the northern hemisphere, is caused by spirochaetes that belong to a group of genospecies called Borrelia burgdorferi sensu lato.2

Pfizer's New Structure Reinforces Potential Split

Organizing commercial operations under Allergan's Brent Saunders is not a preview of an eventual corporate split, but leaves options open, Pfizer says.

Wise rules of medicine that doctors and patients should follow

Orthopedic surgeon Thomas Guastavino often alludes to his “rules of medicine” in the comments.  Here they are in their entirety. Efficacy, safety, and cost are of chief concern. If two treatments are of equal efficacy, choose the safer. If of equal efficacy and safety, choose the cheaper. Cost never trumps efficacy or safety. If you want […]

MHRA recalls St. John's Wort tablets due to contamination that may lead to liver damage

The Medicines & Healthcare products Regulatory Agency in the U.K. is recalling 91,800 packs of St John’s Wort tablets as a precaution because of product contamination that may lead to potential liver damage, according to a medical alert.Various packages of the tablets were found to have levels of toxic pyrrolizidine alkaloid (PA) above the threshold recommended by the Committee on Herbal Medicin...

Regeneron Joins Human Vaccines Project to Improve Global Disease Prevention and Treatment

Regeneron is the latest company to join the Human Vaccines Project Tarrytown, New York, and New York, New York (PRWEB) February 10, 2016 Regeneron Pharmaceuticals Inc. (NASDAQ: REGN) today announced that it has joined the Human Vaccines Project, a public-private partnership to help discover and develop new vaccines and immunotherapies for infectious diseases and cancer. The Human Vaccines Projec...

Scientists Propose "Pumpjack" Mechanism for Splitting and Copying DNA

High-resolution structural details of cells' DNA-replicating proteins offer new insight into how these molecular machines function

Advanced Tri-layer Tubing

Putnam Plastics Corporation, a leader in advanced extrusions and components for minimally invasive medical devices, has developed an advanced tri-layer tubing technology that significantly improves tensile and burst strength, while reducing elongation. Super-Tri tubing is made with a proprietary extrusion process and aids in the prevention of wire lock-up in catheters where guidewires are used.Rea...

Prostate cancer survivors' risk of heart disease studied

(Vanderbilt University Medical Center) Vanderbilt's Cardio-oncology program is focusing on modulating the risk factors for cardiovascular disease in men, especially those receiving androgen deprivation therapy (ADT) to treat their prostate cancer.

Northrop Grumman Demonstrates Continued Progress With its Integrated Topside Advance Development Model

LINTHICUM, Md., Feb. 10, 2016 (GLOBE NEWSWIRE) -- Northrop Grumman Corporation (NYSE:NOC) has successfully demonstrated the ability to conduct simultaneous multi-function military missions as part of its ongoing involvement in the Office of Naval Research (ONR) Integrated Topside (InTop) program. In the demonstrations, conducted in October and November at the Naval Research Labs Chesapeake Bay ...

World Molecular Imaging Congress 2016: “Imaging Biology…Improving Therapy”

Call for Abstracts for WMIC 2016 – March 2, 2016 Deadline Culver City, California (PRWEB) February 10, 2016 The 9th annual meeting of the World Molecular Imaging Society (WMIS), known as the World Molecular Imaging Congress (WMIC), will be held in New York City, NY on September 7 – 10, 2016. The theme for the 2016 meeting is “Imaging Biology…Improving Therapy.” The congress will highlig...

Mylan announces $9.9 billion Meda acquisition

David SalazarSpecialty pharmaceutical company Meda is being acquired by Mylan, expanding Mylan's reach into emerging markets, building on its recent specialty and branded generics acquisitions and creating an OTC division worth about $1 billion.  read more

Nano-caging gives a failed cancer drug new life

BIND Therapeutics could help bring failed cancer drugs back from the dead thanks to some clever molecular packaging.

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