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12:54 EDT 23rd July 2016 | BioPortfolio

New Metformin Rule 'Makes Me Incredibly Happy'

New prescribing guidelines for metformin will make clinicians' lives easier, and they are good for patients, too, says Dr Anne Peters. Medscape Diabetes & Endocrinology

SECURE THE FUTURE Hosting Teens at AIDS 2016

SOURCE: Bristol-Myers Squibb Company DESCRIPTION:SECURE THE FUTURE program is hosting over 100 teens living with HIV at the International AIDS Conference in Durban, South Africa this week.  The young people are coming together to share their stories of living positively.  These teens face unique challenges.  “There is stigma and discrimination in both private and public places,” says Tinash...

Forget Trump. These folks came to the Republican convention to talk obesity

A "Rethinking Obesity" panel at the Republican National Convention urged members of Congress to pass a bill expanding insurance coverage of obesity drugs.

eBioscience PrimeFlow RNA Assay

eBioscience has announced the PrimeFlow RNA Assay, said to be the only flow cytometry assay capable of simultaneous detection of RNA and protein within millions of cells at single-cell resolution. Current flow cytometry applications are limited to antibody-based interrogation of cell surface and intracellular proteins. With the PrimeFlow assay, researchers can incorporate the simultaneous analysi...

Ethics of preparticipation cardiovascular screening for athletes

Preparicipation screening for cardiovascular disease in young competitive athletes is a controversial topic. Moreover, young people not engaged in competitive sports can harbour the same conditions that cause sudden death in athletes. In this Perspectives article, Maron et al. question whether arbitrarily excluding individuals from potentially life-saving clinical screening because they do not en...

Celgene's GED-0301 a new era in Crohn's? Hold your horses

The 160-patient trial tested three doses of GED-0301 (10, 40, or 160mg) against placebo for two weeks, with a primary end point of clinical remission, defined as a Crohn's disease activity index (CDAI) score of less than 150 at day 15 (scores can range...

Pfizer Inc. - Product Pipeline Review - 2015

Recently added to the BioPortfolio report store, Pfizer Inc. - Product Pipeline Review - 2015 is a new report from Global Markets Direct published on 2015-04-21. This 390-page report is available in PDF from $1500. Pfizer Inc. - Product Pipeline Review - 2015 Summary Global Markets Direct’s, ‘Pfizer Inc. - Product Pipeline Review - 2015’, provides an overview of the Pfizer Inc.’s pharmac...

FDA approves Gilead’s Odefsy for treatment of HIV-1 infection

Gilead Sciences has announced that the US Food and Drug Administration (FDA) has approved its TAF-based single tablet regimen Odefsey (emtricitabine, rilpivirine and tenofovir alafenamide) for the treatment of HIV-1 infection in certain patients. read more

The Bristol and Chesterfield Group Submits in Less Than 32 Days

Annapolis, MD, April 04, 2016 --(PR.com)-- The Bristol and Chesterfield Group has had one of their quickest submissions ever. "Miri Trading, specializing in Polaroid Intraoral Dental Cameras and films came to The Bristol and Chesterfield Group in late January. We talked a while to Craig Goldstein, owner of Miri Trading, LLC located in NY," says Matt Elliot a Bristol and Chesterfield Gro...

Cold Spring Harbor Laboratory confers 90th Ph.D.

Senator Tom Harkin and Dr. John Tooze receive Watson School of Biological Sciences honorary degreesCold Spring Harbor, N.Y. – On Sunday, May 1, proud friends and family mingled with distinguished scientists at the 13th commencement ceremony of the Watson School of Biological Sciences at Cold Spring Harbor Laboratory (CSHL). Seven outstanding young scientists were awarded the degree of Doctor of ...

Genetic variants in patients with crohn's disease prevent 'good' gut bacteria from working

(Cedars-Sinai Medical Center) A major type of inflammatory bowel disease (IBD) may be caused in part by genetic variants that prevent beneficial bacteria in the gut from doing their job, according to a new study published today in the journal Science.

Chugai announces Actemra meets primary endpoint in dose interval reduction study in RA patients

Chugai Pharmaceutical Co., Ltd. announced that Actemra subcutaneous injection (Actemra), the humanized antihuman IL─6 receptor monoclonal antibody, successfully met the primary endpoint in a dose interval reduction study (MRA231JP study)

New efficacy data for Pfizer's 4-1BB, OX40 programs

Abstracts published ahead of next month's American Society of Clinical Oncology (ASCO) meeting included data for a pair of next-generation immuno-oncology programs from Pfizer Inc. (NYSE:PFE). The antibodies, PF-5082566 (PF-2566) and PF-04518600, are in Phase I testing.PF-5082566 is an agonist of tumor necrosis factor (TNF) receptor superfamily member 9 (TNFRSF9; 4-1BB; CD137). It was developed us...

DAA non-adherence results in lower virologic response rates

SAN DIEGO —  Non-adherence to novel DAA therapies resulted in a 19% reduction in sustained virologic response at 12 weeks, according to findings presented at Digestive Disease Week 2016. Amber R. Altstadt, PharmD, of the department of pharmacy at Froedtert and The Medical College of Wisconsin in Milwaukee, said that WHO estimated 50% of people do not take chronic medications as prescribed. “T...

Spectroline’s Innovative Radiometer/Photometers are Ideal for 
UV Light Measurement In Laboratory Applications

The Spectroline AccuMAX™ Series of digital radiometer/photometers provide accurate readouts for UV irradiance, visible illuminance and luminance light readings. The AccuMAX XR-1000 and XF-1000 readout units combined with the appropriate UV sensors provide measurements of ultraviolet output of UV-A, UV-B and UV-C. The intensity measurement can then be converted to energy, applicable for most ...

SPLENDA® Brand Supports the American Heart Association's Simple Cooking with Heart™ Initiative

CARMEL, Ind., June 8, 2016 /PRNewswire/ -- SPLENDA® Brand, makers of America's #1 low-calorie sweetener, is announcing that it will once again work with the American Heart Association (AHA) to help support its Simple Cooking with Heart™ initiative.  SPLENDA® Brand and the AHA together will create and distribute tools and resources to educate Americans on how to live ...

PnuVax to acquire inactivated yellow fever vaccine intellectual property from GE Healthcare

Companies to optimize manufacturing process using GE FlexFactory CHALFONT ST. GILES, UK and KINGSTON, ONTARIO, CANADA – 8 June 2016 – PnuVax Incorporated (PnuVax), a vaccine and biopharmaceutical company, and GE Healthcare’s Life Sciences business (NYSE: GE) announced today that they have entered an agreement under which PnuVax can acquire GE Healthcare’s intellectual p...

Intrinsic molecular subtyping enables fine-tuned prognosis and prediction of tumour behaviour in patients with advanced breast cancer

Principal Investigator of Vall d´Hebron Institute of Oncology´s (VHIO) Translational Genomics Group, Team Leader of translational genomics and targeted therapeutics in solid tumours at the August Pi I Sunyer Biomedical Research Institute (IDIBAPS), and...

Impact Of Incorrect Forecasts On New Drug Product Launches

Pharmaceutical companies around the world are under tremendous pressure – from regulators, legislators, payers, and patients – to reduce the cost of drugs. In response to the outcry for cost-cutting, pharmaceutical company leaders are examining every aspect of their business to determine where they can derive savings, particularly when planning for the launch of a new product. Pharmace...

FIBROMYALGIE: Du magnésium pour calmer la douleur et éclaircir le cerveau - Journal of Integrative Medicine

Un magnésium un peu particulier, le magnésium-L-thréonate ou « mmfs-01 », développé par Neurocentria, Inc., une société pharmaceutique, révèle ses premières preuves d'efficacité contre la déficience cognitive légère liée à l'âge. La recherche suggère qu...

Methanogenesis: A radical approach

Amgen developing Soliris biosimilar

Amgen has started a trial of a biosimilar version of Alexion Pharmaceuticals’ Soliris (Eculizumab).

Multiplex immunoassays with Firefly® particle technology

Abcam’s multiplex immunoassays combine unique Firefly® hydrogel technology with Abcam’s high-performance antibodies to simultaneously measure up to 75 different proteins in a mere 12.5 µL of sample. With sensitivity below 1 pg/mL, the assay can provide rapid multiplex data within hours1, even in complex matrices with low target concentrations. Unlike many other multiplex...

Academic-industry collaboration generates elegant way of pinpointing how a new drug exerts beneficial effects

Tested on a newly discovered target and candidate drug for leukemia, the method has broader application Cold Spring Harbor, NY — A collaborative effort by cancer researchers at Cold Spring Harbor Laboratory (CSHL) and chemists at Boehringer Ingelheim (BI), a pharmaceutical firm, has resulted in the identification of a new drug target in leukemia and creation of a candidate drug that hits the tar...

The Immunotherapy Bubble Is Here

EMA Releases Statement on Brexit

The agency says, for now, it’s business as usual. The European Medicines Agency (EMA) says the future location of the agency will be determined by common agreement between representatives of the Member States, according to a July 6, 2016 statement. Until then, EMA says it will be conducting business as usual, and the outcome of the June 23 referendum will not affect the agency’s operat...

Arquer Diagnostics Appoints Louise Flintoft as Product Manager

Appointment strengthens senior team in preparation for EU regulatory approval and commercial launch of Mcm5-ELISA test Sunderland, UK, 13 July 2016: Arquer Diagnostics Ltd (Arquer), a diagnostic company which has developed a high sensitivity, high specificity, ELISA-based urine test for cancer, today announced the appointment of Louise Flintoft to the post of Product Manager. Louise’s ap...

Blue Latitude Health Expands to US and Opens New Office in New York City

LONDON and NEW YORK, July 13, 2016 /PRNewswire/ -- New US Office to Provide Clients With Global and Regional Strategic Consultancy Services and Build new Relationships in the Pharma, Life Sciences and Healthcare Sector  Blue Latitude Health ("BLH"), a privately owned creative marketing consultancy specialising in healthcare, is pleased to announce the opening of a new US office in New York ...

Lilly and Boehringer Ingelheim Announce Clinical Trial Collaboration in Metastatic Breast Cancer

INDIANAPOLIS, July 13, 2016 /PRNewswire/ -- Eli Lilly and Company (NYSE: LLY) and Boehringer Ingelheim today announced a new collaboration on a Phase 1b study that will evaluate the safety and tolerability of abemaciclib (LY2835219), Lilly's cyclin-dependent kinase (CDK) 4 and CDK 6 inhibitor, in combination with BI 836845, Boehringer Ingelheim's insulin-like growth factor (IGF)-1/IGF-2 ligan...

Express Scripts Announces Early Tender Results and Upsizing of Maximum Tender Offers

ST. LOUIS, July 14, 2016 /PRNewswire/ -- Express Scripts Holding Company (NASDAQ: ESRX) (the "Company" or "Express Scripts") today announced the early tender results for its previously announced tender offers (the "Maximum Tender Offers") to purchase for cash up to an aggregate principal amount of the debt securities listed in the table below (collectively, the "Notes" and each a "series") that wi...

In Rush to Serve More Veterans, VA Opens Door to Disability Fraud

Disability benefits have soared as the embattled Veterans Affairs department expands coverage and streamlines the claims process. Now, some critics say the reduced evidence requirements can mean claims get padded.

5 Nutrition Facts misconceptions that sabotage patient health

The fight against diabetes and heart disease also means fighting nutritional misunderstandings and offering sound advice to patients. A new video helps dispel common misconceptions about the Nutrition Facts label found on food packages and offers physicians guidance on how to educate their patients. Designed to help patients better understand what they are consuming and make more informed deci...

Kirit Patel, ‘giant of independent community pharmacy’, dies aged 66 years

Kirit Patel, co-founder and chief executive of the Day Lewis Group of high street pharmacies, has died suddenly on 16 July 2016 at the age of 66 years.

F2G Names CFO

F2G Ltd., a UK-based antifungal drug discovery and development company, has appointed Ralf Schmid chief financial officer. Schmid carries 20...      Related StoriesPositive Tagrisso Data Boost AstraZeneca's Lung Cancer AmbitionsPureTech Makes Senior AppointmentsIndustry Veteran Peter Chambré Joins Cancer Research UK 

GE Healthcare eyeing more cell and gene therapy production tech supplier takeovers

GE Healthcare has hinted that more gene and cell therapy acquisitions will follow its takeover of the Biosafe Group.

PureFormulas Solidifies Partnership With USPS by Adding Sunday Pick-Up of Orders

PureFormulas Solidifies Partnership With USPS by Adding Sunday Pick-Up of Orders

BRIEF-Eli Lilly, U.S. FDA expand indication for type 2 diabetes treatment Synjardy

* U.S. FDA expands indication for type 2 diabetes treatment Synjardy (empagliflozin/metformin hydrochloride) to include treatment-naïve adults

EC approves AstraZeneca's diabetes combo Qtern

AstraZeneca plc (LSE:AZN; NYSE:AZN) said the European Commission approved Qtern saxagliptin/dapagliflozin to improve glycemic control in adults with Type II diabetes for whom metformin and/or sulfonylurea, plus either Qtern component alone, do not provide adequate control. It is also indicated for patients already receiving a free combination of Qtern's components.AZ said it was the first EU appro...

China Resources Poised to Buy Genesis Care

China Resources Group is leading a consortium poised to acquire a stake in Australian cancer therapy provider Genesis Care, the first big health care deal following last year’s free-trade agreement between the two countries.

AZ’s diabetes combination Qtern approved in Europe

The European Commission has granted marketing approval to a new combination pill from AstraZeneca to treat type 2 diabetes. Qtern combines the company’s existing DPP-4 inhibitor drug Onglyza (saxagliptin) with its SGLT2 inhibitor Forxiga (dapagliflozin), the first ever to combine treatments from these two classes. The approval is good news, as the FDA rejected the combination in October last ye...

Teenager born with no limbs forced to live in a plastic bowl – Mirror.co.uk

Mirror.co.ukTeenager born with no limbs forced to live in a plastic bowlMirror.co.ukA teenage girl born without limbs lives her life in a plastic bowl because of a mysterious condition that stopped her arms and legs developing properly. Rahma Haruna is a bright, happy girl, despite being practically limbless and in constant pain.Rahma, the Nigerian teen who lives in a plastic bowl, dreams of runni...

Galenica to acquire Relypsa to strengthen its Business unit Vifor Pharma

Vifor Pharma Ltd. / Galenica to acquire Relypsa to strengthen its Business unit Vifor Pharma . Processed and transmitted by NASDAQ OMX Corporate Solutions. The issuer is solely responsible for the content of this announcement. Galenica and Relypsa announce agreement for Galenica to acquire Relypsa. Acquisition strengthens Galenica's Business unit, Vifor Pharma - an important...

EU orphan status for Cell Medica drug

London, UK-based Cell Medica has received European Commission orphan drug designations for its lead cancer immunotherapy CMD-003 (baltaleucel-T).

Consumer Health Guide Names 2016's 10 Greatest Meal Replacement Shakes

NEW YORK, July 21, 2016 /PRNewswire/ -- Thevery best meal replacements are ranked in terms of quality of ingredients, cost, consumer reviews, kinds of money back return policies, and effectiveness. Photo - http://photos.prnewswire.com/prnh/20160714/389637 Over 100 meal replacements and counting have been studied to ensure people know which are the best, and why. In this comprehensive websi...

More changes at the top of Perrigo

Ireland-incorporated Perrigo has announced that Douglas Boothe, the general manager of its Rx Pharmaceuticals…

Remsima Stars In Orion Pharma’s First Half

Sales in Scandinavia of the biosimilar infliximab drove Orion’s specialty business in the first six months of 2016.      Related StoriesRemsima Stars In Orion Pharma’s First HalfRoche Sees Cancer Combos Start To DeliverChanges Brewing At Bayer, But Pharma Strategy Remains On Point 

Evoke Pharma (EVOK) - Early Post-Morten

We recently publishedterse commentary regarding the failure of EVK-001 to treat female diabetic gastroparesis. In recent press releases, Evoke pointed to an alleged bifurcation of results:28 of 41 sites reported statistically significant benefit in favor of EVK-001 (p=0.006)13 of 41 sites reported statistically significant benefit in favor of Placebo (p=0.002).Evoke management then announced an at...

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