Articles about Biotechnology, Pharmaceutical and Healthcare

00:45 EDT 1st July 2015 | BioPortfolio

Latest Articles on life science, biotechnology, pharmaceutical and healthcare topics and current issues.

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Tuesday 30th June 2015

[Articles] Mutations in in a Belgian cohort of Alzheimer's disease patients: a targeted resequencing study

We propose that a low-frequency variant can explain the association between ABCA7 and Alzheimer's disease, and the evidence of loss-of-function mutations in this risk gene suggests that partial loss-of-function of ABCA7 could be a potential pathogene...

[Comment] Expanding the genomic roadmap of Alzheimer's disease

Alzheimer's disease has a strong heritable component. Early genetic studies of the molecular basis of Alzheimer's disease led to the discovery of rare (less than one per 10 000 population) and highly penetrant mutations in the genes encoding amyloi...

Monkey Business

Travel to Bangladesh to meet the Bedey, a band of river nomads, and their trained macaques, which perform shows and seldom transmit a monkey virus to their handlers.


See how William Beebe and Otis Barton descended to the ocean's depths in an early submersible designed to allow access to the mysterious lifeforms inhabiting the deep sea.


Scientist to Watch Shawn Douglas explains the annual competition he established to introduce students to molecular programming.

You Gutless Worm

Meet the digestive tract-lacking oligochaete that has fueled Max Planck research Nicole Dubilier's interest in symbiosis and marine science.

Book Excerpt from Faith vs. Fact

In Chapter 1, “The Problem,” author Jerry Coyne sets the historical stage for his suggestion that science and religion are not compatible and never will be.

Half Mile Down, 1934

In his bathysphere, William Beebe plumbed the ocean to record-setting depths.

The War Rages On

Conflict between science and religion continues, with effects on health, politics, and the environment.

Staying Active in the Lab

Retiring as a professor, and even shutting down your own lab, doesn’t necessarily mean quitting research.

Breaking Down Barriers

Finding and recruiting diverse populations for clinical studies

Tools for Drools

A general guide to collecting and processing saliva

Shawn Douglas: DNA Programmer

Assistant professor, Cellular and Molecular Pharmacology, University of California, San Francisco. Age: 34

Sold on Symbiosis

A love of the ocean lured Nicole Dubilier into science; gutless sea worms and their nurturing bacterial symbionts keep her at the leading edge of marine microbiology.

Sponging Up Phosphorus

Symbiotic bacteria in Caribbean reef sponges store polyphosphate granules, possibly explaining why phosphorous is so scarce in coral reef ecosystems.

Metazoans in the DNAi Club

A chance discovery results in the first report of DNA-based gene silencing in an animal.

1 + 1 = 1

Nutrient levels in soil don’t add up when food chains combine.

How to Make a New Species

Scientists mutate a mating pheromone and its corresponding receptor in yeast to promote speciation.

When Does a Smart Mouse Become Human?

Ethical issues attend the creation of animal-human chimeras.

High-Flying Ducks

Five species of waterfowl have evolved a variety of adaptations to adjust to the high altitude of South America’s Lake Titicaca.

Hunting Off the Hook?

Historical data sheds new light on the possible causes of southern sea lion decline in the Falkland Islands.

Brrrr-ying the Results

Holding laboratory mice at temperatures lower than those the animals prefer could be altering their physiology and skewing experimental results.

The Lies That Scars Tell

Macaque trainers in Bangladesh are often bitten by their monkeys, but rarely infected by a particular simian retrovirus.

Intelligence Gathering

Disease eradication in the 21st century

Driven to Extinction

The eradication of smallpox set the standard for the global elimination of a devastating infectious disease. Will the ongoing polio and guinea worm campaigns be as successful?