Articles about Biotechnology, Pharmaceutical and Healthcare

00:56 EDT 31st October 2014 | BioPortfolio

Latest Articles on life science, biotechnology, pharmaceutical and healthcare topics and current issues.

Showing News Articles 1–25 of 39,000+

Thursday 30th October 2014

[Articles] Use of [18F]-FDG PET to predict response to neoadjuvant trastuzumab and docetaxel in patients with HER2-positive breast cancer, and addition of bevacizumab to neoadjuvant trastuzumab and docetaxel in [18F]-FDG PET-predicted non-responders (AVAT

In patients with HER2-positive breast cancer, early PET assessment can help to identify non-responders to neoadjuvant docetaxel plus trastuzumab therapy. In these patients, the addition of bevacizumab can increase the proportion of patients achieving...

[Comment] Predicting pathological complete response in breast cancer early

Baseline staging with [18F]-fluorodeoxyglucose ([18F]-FDG) PET-CT scans can enable better patient selection before randomisation in neoadjuvant trials by excluding those patients with occult distant metastases and poor prognosis. A second potential r...

[Articles] Clinical follow-up compared with self-assessment of outcome after medical abortion: a multicentre, non-inferiority, randomised, controlled trial

Self-assessment was non-inferior to routine follow-up and could save resources.

[Comment] Follow-up after medical abortion: does simple equal safe?

In The Lancet, Kevin Sunde Oppegaard and colleagues report the findings of a multicentre European non-inferiority trial of 924 women who underwent early medical abortion and were randomised to clinical routine follow-up at 1–3 weeks (n=466), or hom...

[Articles] Safety and immunogenicity of a modified-vaccinia-virus-Ankara-based influenza A H5N1 vaccine: a randomised, double-blind phase 1/2a clinical trial

The MVA-based H5N1 vaccine was well tolerated and immunogenic and therefore the vaccine candidates arising from the MVA platform hold great promise for rapid development in response to a future influenza pandemic threat. However, the immunogenicity o...

[Comment] Modern twist on a classic formula for influenza vaccination

The most effective method of protection against disease and death caused by influenza viruses is vaccination. In a recent study, vaccination was calculated to prevent 80 000 influenza-related hospital admissions in the USA (2012–13 season), altho...

Fresh strike date announced by unions in pay dispute

The NHS is to face a second day of strike action, as unions continue their dispute with the government over health service pay.

Remote ischaemic preconditioning and other stories . . .

It’s the squeeze that protects organs. Remote ischaemic preconditioning seems too good, and too simple, to be true. The latest evidence comes from a trial (Heart 2014,...

Diagnosis and management of gallstone disease: summary of NICE guidance

Gallstone disease is common—10-15% of adults in Western populations are thought to have the condition.1 2 Concerns about inappropriate variation in the management of gallstones have led to the...

TNIB to Start 90-Day HIV/AIDS Trial in Nigeria

TNI BioTech Inc., ("TNIB"), headquartered in Orlando, Florida and Dublin, Ireland, a specialty pharmaceutical company involved in the manufacture, distribution and marketing of novel, patented therapies to combat chronic, life-threatening diseases through the activation and modulation of the body's immune system, through its wholly owned subsidiary TNI BioTech International Ltd., announces the ini...

Authors' reply to Mosholder and colleagues

We are glad that Mosholder and colleagues agree that psychotropic poisonings increased, not decreased, after the warnings and news reports.1 2 We believe that debate in this area is instructive for...

US nurse says she will fight Ebola quarantine

The US nurse who cared for patients with Ebola virus disease in west Africa and is now being held in quarantine in her home in Maine said on 29 October that she would challenge her detention in...

Antibiotics and sudden death in adults taking renin-angiotensin system blockers

Adverse drug reactions have been associated with up to 10% of hospital admissions in older adults,1 a considerable number of which involve drug-drug interactions. Traditionally, information about...

FDA Approves Generic Alzheimer's Drug

TWi Pharmaceuticals Inc. announced that it has received final approval from the United States Food and Drug Administration (FDA) on its Abbreviated New Drug Application (ANDA) for Donepezil Hydrochloride Tablets USP, 23 mg, the generic equivalent to Eisai Inc.'s Aricept 23mg.

Human medicines European public assessment report (EPAR): Nevirapine Teva, nevirapine, Revision: 5, Authorised

Human medicines European public assessment report (EPAR): Lucentis, ranibizumab, Revision: 21, Authorised

‘Treasure in Saliva’ May Reveal Diseases Early Enough to Treat

Read more about ‘Treasure in Saliva’ May Reveal Diseases Early Enough to TreatComments

AstraZeneca's Diabetes Treatment Gets FDA Approval

AstraZeneca announced that the US Food and Drug Administration (FDA) has approved once-daily Xigduo XR (dapagliflozin and metformin hydrochloride extended-release) for the treatment of adults with type 2 diabetes. Xigduo XR combines two anti-hyperglycaemic agents with complementary mechanisms of action, dapagliflozin (trade name in the US,

Microsoft Unveils Fitness Gadget, Health Tracking

Read more about Microsoft Unveils Fitness Gadget, Health Tracking

Whistleblower calls for support to stop nurses quitting profession

Leading nurse whistleblower Helene Donnelly has urged the profession to support fellow workers to ensure “much-needed” nurses and carers do not leave their jobs.

Nurse of the Year announced at glittering awards do

A specialist in both cancer and dementia care was last night revealed as this year’s Nursing Times Nurse of the Year in front of hundreds of other members of the profession.

Body Clock Gene May Impact Drug Delivery

Read more about Body Clock Gene May Impact Drug DeliveryComments

Research Reveals Fish Are Smarter Than We Thought

Read more about Research Reveals Fish Are Smarter Than We Thought

NeuroDerm Announces Positive Phase 2 Results of Parkinsons Vaccine

NeuroDerm Ltd., a clinical-stage pharmaceutical company developing drugs for central nervous system (CNS) diseases, announced that patients with moderate to severe Parkinson’s disease who received continuous, subcutaneous doses of liquid levodopa/carbidopa (LD/CD) (ND0612L) exhibited clinically significant reduction in fluctuations of plasma levodopa concentrations compared to patients receiving...

New national sperm bank will 'build families'

A national sperm bank has opened to help meet increasing demand for donors in the UK.


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