Syndicated Content about Biotechnology, Pharmaceutical and Healthcare

06:12 EDT 23rd October 2014 | BioPortfolio

Latest global life science, pharmaceutical and healthcare news syndicated from over 50 publishers. 

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Thursday 23rd October 2014

BRIEF-Straumann CFO sees 2014 EBIT margin between 20 and 21 pct

* CFO expects an EBIT margin for 2014 between 20 and 21 percent Further company coverage:

Pharma pulls together for Ebola vaccine; JnJ invests $200m

UPDATE 2-Straumann lifts full-year outlook after strongest sales growth in 15 quarters

* Q3 sales rise 7.3 pct to 164.3 mln Sfr vs 158 mln f'cast

Relypsa seeks FDA nod for patiromer to treat hyperkalemia

Investors, however, only gave Relypsa a 1% boost on 22 October, before the stock closed down 5 cents at $18.72.

GSK climbs as structural overhaul revealed

Medicines are not goods like any other, says new EU President

Medicines are not goods like any other, says new EU President

Biogen Idec third-qtr net rockets 76% but shares slump

US biotech firm Biogen Idec saw its share price plunge 7% to $303.51, after its posted third-quarter 2014 financial results, despite revealing that net income of $856.9 million (a year-on-year-leap of 76%), or $3.62 per share, beat consensus analysts...

UK’s NICE backs another use for Bayer’s Xarelto

In draft guidance published today for consultation, the UK’s health costs watchdog the National Institute for Health and Care Excellence (NICE) has recommended German pharma major Bayer’s Xarelto (rivaroxaban) as an option for preventing blood cl...

Enigma and Beijing Leadman Form Infectious Disease Diagnostic JV

Enigma Diagnostics of England announced a joint venture with Beijing Leadman Biochemistry for China development of Enigma's molecular diagnostic point-of-care (PoC) infectious disease test. Beijing Leadman will market the Enigma Mini Laboratory PoC m...

UPDATE 2-Safran shares rise on Q3 revenues, confident outlook

* Comments ease concerns over aviation market (Adds share reaction, quotes, CEO transition comments)

Alkermes long-acting schizophrenia drug under FDA scrutiny

Shares of Alkermes bumped up 2.26% on 22 October on the news, before closing at $44.66, up 86 cents, or about 2%.

Drugmakers may need indemnity for fast-tracked Ebola vaccines

LONDON/GENEVA (Reuters) - Drugmakers are looking for some kind of indemnity from governments or multilateral agencies for the widespread emergency use of new Ebola vaccines in Africa.

North Korea to bar foreign tourists over Ebola concerns: tour operators

SEOUL (Reuters) - North Korea will bar entry to foreigners on tourist trips from Friday, because of worries over the spread of the deadly Ebola virus, operators of tours to the isolated country told Reuters.

Sample size calculation for the one‐sample log‐rank test

In this paper, an exact variance of the one‐sample log‐rank test statistic is derived under the alternative hypothesis, and a sample size formula is proposed based on the derived exact variance. Simulation results showed that the proposed sample ...

Rapid modelling of cooperating genetic events in cancer through somatic genome editing

Cancer is a multistep process that involves mutations and other alterations in oncogenes and tumour suppressor genes. Genome sequencing studies have identified a large collection of genetic alterations that occur in human cancers. However, the determ...

Spatially resolved magnetic field structure in the disk of a T Tauri star

Magnetic fields in accretion disks play a dominant part during the star formation process but have hitherto been observationally poorly constrained. Field strengths have been inferred on T Tauri stars and possibly in the innermost part of their accre...

Productivity limits and potentials of the principles of conservation agriculture

One of the primary challenges of our time is to feed a growing and more demanding world population with reduced external inputs and minimal environmental impacts, all under more variable and extreme climate conditions in the future. Conservation agri...

In vivo engineering of oncogenic chromosomal rearrangements with the CRISPR/Cas9 system

Chromosomal rearrangements have a central role in the pathogenesis of human cancers and often result in the expression of therapeutically actionable gene fusions. A recently discovered example is a fusion between the genes echinoderm microtubule-asso...

Resolving the long-standing enigmas of a giant ornithomimosaur Deinocheirus mirificus

The holotype of Deinocheirus mirificus was collected by the 1965 Polish–Mongolian Palaeontological Expedition at Altan Uul III in the southern Gobi of Mongolia. Because the holotype consists mostly of giant forelimbs (2.4 m in length) with scapulo...

Luminal signalling links cell communication to tissue architecture during organogenesis

Morphogenesis is the process whereby cell collectives are shaped into differentiated tissues and organs. The self-organizing nature of morphogenesis has been recently demonstrated by studies showing that stem cells in three-dimensional culture can ge...

Precision microbiome reconstitution restores bile acid mediated resistance to Clostridium difficile

The gastrointestinal tracts of mammals are colonized by hundreds of microbial species that contribute to health, including colonization resistance against intestinal pathogens. Many antibiotics destroy intestinal microbial communities and increase su...

Cessation of CCL2 inhibition accelerates breast cancer metastasis by promoting angiogenesis

Secretion of C–C chemokine ligand 2 (CCL2) by mammary tumours recruits CCR2-expressing inflammatory monocytes to primary tumours and metastatic sites, and CCL2 neutralization in mice inhibits metastasis by retaining monocytes in the bone marrow. He...

Structure and insights into the function of a Ca2+-activated Cl− channel

The X-ray crystal structure of a eukaryotic Ca2+-activated chloride channel, BEST1, and its function in liposomes are described; the structure shows that Ca2+ binds to the cytosolic region of this pentameric channel and reveals that the pore is appro...

Developmental biology: Cells unite by trapping a signal

Gradients of fibroblast growth factors often induce cells to adopt different fates. A study in zebrafish embryos reveals another, unexpected role when the factors are trapped in small spaces by a special arrangement of cells.

Cancer: Metastasis risk after anti-macrophage therapy

Blocking the activity of macrophages may delay the spread of cancer. But new findings show that these immune cells can rapidly rebound to tumours after therapy withdrawal, accelerating lethal metastasis in mice.

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