Syndicated Content about Biotechnology, Pharmaceutical and Healthcare

07:14 EDT 1st November 2014 | BioPortfolio

Latest global life science, pharmaceutical and healthcare news syndicated from over 50 publishers. 

Showing News Articles 1–25 of 410,000+

Saturday 1st November 2014

Wie GoPro, JinkoSolar, SolarCity, Gilead Sciences, World Wrestling Entertainment und Twitter für Gesprächsstoff sorgten

Das hat die BSNgine heute ausgewiesen GPRO: GoPro am 31.10. 12,97%, Volumen 165% normaler Tage , ZJS1: JinkoSolar am 31.10. 6,98%, Volumen 92% normaler Tage , 0SC: SolarCity am 31.10. 5,06%, Volume...

Wie Infineon, Bayer, E.ON , Linde, Fresenius Medical Care und Merck für Gesprächsstoff im DAX sorgten

Das hat die BSNgine heute ausgewiesen IFX: Infineon am 31.10. 6,23%, Volumen 209% normaler Tage , BAYN: Bayer am 31.10. 3,18%, Volumen 169% normaler Tage , EOAN: E.ON am 31.10. 3,08%, Volumen 121% ...

Irvine Pharma Building CRO/CMO Facility in Hangzhou

Irvine Pharmaceutical Services, a California company offering cGMP contract development and parenteral manufacturing services, announced plans to open a new facility in Hangzhou, China. This newly built, state-of-the-art facility will encompass 115,0...

BioChain to Distribute Clinical Genomics' Cancer Test in China

BioChain, a diagnostics company with operations in San Francisco and China, has become the exclusive China distributor of Clinical Genomics' colorectal cancer screening technology. Clinical Genomics of Australia has marketed Insure FIT®, a fecal ...

BCOR–CCNB3 fusions are frequent in undifferentiated sarcomas of male children

Friday 31st October 2014

The Changing Landscape of Branding Pharmaceutical Assets

The landscape in which drugs are named is increasingly complex due to rapid changes in technology, consumer expectations and market competition for trademarks. But one of the biggest factors affecting how companies now name their products is ...

Hepatic Impairment Studies in Phase I-IIa

Innovative patient pharmacology services is a unique scientific/medical and operational model that can be used to conduct studies in patients with hepatic impairment following the same guidelines used in traditional Phase I or Phase IIa trial...

Judge rejects isolation for U.S. nurse who treated Ebola patients

FORT KENT Maine (Reuters) - A Maine judge ruled on Friday that a U.S. nurse who treated victims of Ebola in West Africa does not need to be confined to her home, declaring Ebola fears in the United States "not entirely rational."

c-Abl antagonizes the YAP oncogenic function

Glucocorticoids promote structural and functional maturation of foetal cardiomyocytes: a role for PGC-1α

Granzyme B-induced mitochondrial ROS are required for apoptosis

DAPK2 is a novel regulator of mTORC1 activity and autophagy

Autophagy and regulation of cilia function and assembly

Loss of c-REL but not NF-κB2 prevents autoimmune disease driven by FasL mutation

UPDATE 4-Judge rejects isolation for U.S. nurse who treated Ebola patients

(Adds nurse's quote, details on Pentagon civilians, Oregon woman hospitalized, Louisiana agreement on Ebola waste)

Retraction: A histone lysine methyltransferase activated by non-canonical Wnt signalling suppresses PPAR-γ transactivation

Retraction: Cytokines suppress adipogenesis and PPAR-γ function through the TAK1/TAB1/NIK cascade

Retraction: DEAD-box RNA helicase subunits of the Drosha complex are required for processing of rRNA and a subset of microRNAs

Corrigendum: PGC-1α mediates mitochondrial biogenesis and oxidative phosphorylation in cancer cells to promote metastasis

Autoinhibition and cooperative activation mechanisms of cytoplasmic dynein

Furuta and colleagues report that single dynein molecules are kept in an autoinhibited state through the stacking of their two head domains. This autoinhibition is relieved when dynein molecules assemble together on cargo.

A breast cancer stem cell niche supported by juxtacrine signalling from monocytes and macrophages

Weinberg and colleagues report that monocytes and macrophages interact with stem-like human mammary epithelial cells to create a breast cancer stem cell niche.

ASPP2 controls epithelial plasticity and inhibits metastasis through β-catenin-dependent regulation of ZEB1

Lu and colleagues report that ASPP2 induces mesenchymal–epithelial transition and inhibits cancer cell invasion and metastasis by preventing the β-catenin-mediated upregulation of ZEB1.

Cyclin C is a haploinsufficient tumour suppressor

Through gene knockout experiments, Sicinski and colleagues reveal a role for cyclin C as a haploinsufficient tumour suppressor in T-cell acute lymphoblastic leukaemia, acting through phosphorylation of intracellular Notch1, mediating its degradation.

Selective VPS34 inhibitor blocks autophagy and uncovers a role for NCOA4 in ferritin degradation and iron homeostasis in vivo

Murphy and colleagues generate an inhibitor of the lipid kinase VPS34, which they use to uncover autophagy substrates. One of their targets, NCOA4, regulates iron homeostasis by binding ferritin heavy chain-1 and targeting ferritin to autolysosomes.

Stat3 controls cell death during mammary gland involution by regulating uptake of milk fat globules and lysosomal membrane permeabilization

Lysosomal membrane permeabilization releases cathepsins to promote cell death and mammary gland involution. Sargeant et al. report that Stat3-driven phagocytic uptake of fatty acids in milk triglycerides permeabilizes lysosomes to induce cell death...


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