Executive Summary

Despite important advances in understanding the molecular basis of cancer, few treatments have been devised to specifically target the known defects in tumor cells. Standard chemotherapy or radiation treatments are inherently non-selective and kill normal cells along with malignant ones. Effective future treatments depend of developing drugs that target individual abnormalities in specific tumor cells. Specially promising new drug classes under development for treatment of cancer include monoclonal antibodies and angiogenesis inhibitors. 

Despite early enthusiasm for angiogenesis inhibitors as safe and effective anticancer drugs, results of several completed Phase III and Phase II trials have been disappointing. New strategies have been developed to overcome these previous mistakes. Since the early failure of drugs such as Avastin, Erbitux, SU5416, Marimastat, Endostatin and Angiostatin, new clinical trials have commenced that will define whether the anti-angiogenetic and vascular targeting strategies will hold. 

"BSG Analytical Tool: Antiangiogenesis & Vascular Targeting" offers a unique tool (database and reports) for analyzing the vast amount of strategic possibilities that have emerged in anticancer antiangiogenesis and vascular targeting. It is at the same time a map of the research and development, a history of the achievements up to date, and a guide pointing out the directions of the future. This tool provides you with an immense amount of information structured and analyzed to assist you in your work. Additionally, BioSeeker Group has developed a CD-ROM searchable database, which is highly updated to reflect the most recent advances in the field of cancer immunotherapy development, in order to help you perform your own analysis, go back to the source data for in-depth information, and present the research and development in tables and graphs suited for your own specific purposes. 

A significant advantage with BioSeeker Group CD-ROM searchable databases is that they provide you with well-structured information. Each pipeline drug/project has been carefully defined and classified in categories and subcategories. The main categories include therapy type, effect, mechanism of action (molecular target), indication, stage of development etc. These categories are further organized and classified in sub-categories. In comparison with other available databases, BioSeeker Group CD-ROM searchable databases gives better overview and specific search capabilities. 

Our hope is that this product will assist you in your struggle of finding the right partners, optimizing your licensing deals, wisely choosing which projects give you the best competitive advantage, and assuring you that your decisions have been based on the most accurate, validated and precise facts available. 

Format: CD-ROM

Published: Feb 2004 

Publisher: BioSeeker 

To order go to this URL: http://www.bioportfolio.com/cgi-bin/acatalog/BioSeeker.html#a154