Researchers in several key markets are exploiting advanced techniques, including DNA microarrays, to assess potentially harmful compounds faster and with greater accuracy than animal testing or in vitro assays. Known as toxicogenomics, this exciting field is transforming how toxicologists think and act. The market implications of this research are especially significant for suppliers to the drug industry where toxicogenomics may be used to reduce misleading toxicity results and streamline drug development. Based on a 38-question survey of over 300 life scientists involved in toxicogenomics, this report provides a look at service providers, informatics products, microarrays and databases from the end-user's perspective. By understanding the actual experiences, preferences and expectations of these researchers, life science suppliers can better position themselves and appeal to the diverse needs of their target market.  

The major objectives of this report are as follows:

> Determine the objectives and challenges of toxicology and toxicogenomics studies.

> Identify commonly used toxicology methodologies.

> Determine proportion of researchers who outsource toxicogenomics activities and their vendor selection criteria.

> Assess key elements of toxicogenomics experimental design.

> Estimate current and future toxicogenomics sample throughput.

> Identify preferred suppliers of toxicogenomics products and services.

> Assess level of satisfaction with current toxicogenomics products.

> Ascertain unmet user needs in toxicogenomics product and service market.  

Report Highlights

The Market for Toxicogenomics Products & Services contains over 70 charts and/or tables and over 40 cross-tabulations for the 38 survey questions.  Below is a glimpse of the key findings derived from just a few of the survey questions: 

"           The most frequently used toxicology methods are cell-based assays, microarrays (DNA or protein), real-time quantitative RT-PCR and whole animal assays. (Question 3) 

"           The majority of the respondents' toxicogenomics experiments are performed in their lab (47%) or at an institutional or departmental core facility (27%). (Question 8) 

"           The most significant challenges that respondents experience when designing their toxicogenomics experiments are "generating reproducible results" (22%) and "obtaining enough samples for statistical relevance" (20%). (Question 21) 

"           While 35% of the respondents who use DNA microarrays in their toxicogenomics research think that the number of DNA microarrays they hybridize or analyze will stay the same, another 46% believe it will increase. (Question 24) 

"           For the DNA microarrays used in their toxicogenomics research, over 50% of the survey respondents use an Affymetrix GeneChip and 28% print them in their lab.  (Question 28) 

"           Overall, researchers are least satisfied with the literature search, script building and price of their data analysis software. (Question 32) 

April 2003, 193 Pages 

Publisher: BioInformatics 

To order go to this URL: http://www.bioportfolio.com/cgi-bin/acatalog/copy_of_bioinformatics_1.html#a41