Based on a 33-question survey, Nuclear Magnetic Resonance (NMR) is the sixth of six titles in the series, The Tools & Techniques of Drug Discovery, and focuses specifically on NMR technology to help suppliers better serve and satisfy this market. Structural data is critical in determining how a potential drug will bind with a target molecule. Nuclear magnetic resonance screening of multiple targets and the rational design of high-affinity ligands are now a main focus of drug discovery efforts. The objective of this report is to provide understanding of how researchers are applying various NMR spectroscopy disciplines within drug discovery, including library screening, rational design of high-affinity ligands and structure-activity relationships. Nuclear Magnetic Resonance will explore end-users' satisfaction with industry innovations such as the integration of sophisticated radio frequency, improved digital electronics, automated probe/sample handling technologies and advanced bioinformatics. It will also assess researcher's needs for increased sensitivity and greater throughput capacity, which is essential for companies wishing to increase the efficiency of the drug discovery process.  

The major objectives of this report are as follows:

> Examine the use and application of NMR in drug discovery research

> Determine what features are most influential in purchasing decisions

> Identify the preferred suppliers of NMR spectrometers and related products and services (including software packages)

> Establish the parameters for quality in NMR products and services

> Understand -- from the user's perspective -- the level of satisfaction with current products and any unmet needs in the area of NMR spectroscopy 

Date: May 2002 Format: Hard Copy & PDF Email Pages: 119 Category:  Drug Discovery 

Publisher: BioInformatics 

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