Losartan Potassium and Hydrochlorothiazide Tablets, USP | Losartan Potassium and Hydrochlorothiazide


| |
Losartan Potassium and Hydrochlorothiazide (n=858) |
Placebo (n=173) |
|
Body as a Whole
|
|
|
| Abdominal pain |
1.2 |
0.6 |
| Edema/swelling |
1.3 |
1.2 |
|
Cardiovascular
|
|
|
| Palpitation |
1.4 |
0 |
|
Musculoskeletal
|
|
|
| Back pain |
2.1 |
0.6 |
|
Nervous/Psychiatric
|
|
|
| Dizziness |
5.7 |
2.9 |
|
Respiratory
|
|
|
| Cough |
2.6 |
2.3 |
| Sinusitis |
1.2 |
0.6 |
| Upper respiratory infection |
6.1 |
4.6 |
|
Skin
|
|
|
| Rash |
1.4 |
0 |
| Study 1 |
HCTZ |
Losartan |
Lisinopril |
| Cough |
25% |
17% |
69% |
| Study 2 |
Placebo |
Losartan |
Lisinopril |
| Cough |
35% |
29% |
62% |



Manufacturer
NorthStar Rx LLC
Active Ingredients
Source
- U.S. National Library of Medicine
- DailyMed
- Last Updated: 4 May 2013
Drugs and Medications
Losartan potassium and hydrochlorothiazide [Greenstone LLC]
losartan potassium and hydrochlorothiazide tablets, USP
Losartan potassium and hydrochlorothiazide [Aurobindo Pharma Limited]
Losartan Potassium and Hydrochlorothiazide Tablets, USP
Losartan potassium [Aurobindo Pharma Limited]
Losartan Potassium Tablets USP
Losartan potassium [Greenstone LLC]
Losartan potassium and hydrochlorothiazide [Sandoz Inc.]
SANDOZLosartan Potassium and Hydrochlorothiazide Tablets 50/12.5 mgLosartan Potassium and Hydrochlorothiazide Tablets 100/12.5 mgLosartan Potassium and Hydrochlorothiazide Tablets 100/25 mg
Clinical Trials
Hydrochlorothiazide (+) Losartan Potassium vs. Amlodipine Comparative Study
An efficacy and safety study of hydrochlorothiazide (+) losartan potassium compared to amlodipine at week 12 in Korean patients with essential hypertension
The objective of this study was to prove the bioequivalence of losartan potassium/hydrochlorothiazide 100/25 mg tablet under fed conditions.
Evaluate blood pressure after 6 weeks of treatment with COZAAR plus.
A Study of Losartan Compared to Losartan/HCTZ in Pediatric Patients With Hypertension
The purpose of this study is to test the safety and effectiveness of Losartan as compared to Losartan/HCTZ in pediatric patients (6 to 17 years) with high blood pressure.
LAAS (Losartan Anti-Atherosclerosis Study)
The primary objective of this study is to evaluate efficacy, arterial stiffness measured by PWV of Losartan potassium group compared to Carvedilol group after 24 weeks of treatment in pati...
PubMed Articles
The treatment of morning hypertension has not been established. We compared the efficacy and safety of a losartan/hydrochlorothiazide (HCTZ) combination and high-dose losartan in patients with morning...
The effects of clinically relevant concentrations of anti-hypertensive agents on lipopolysaccharide (LPS)-induced interleukin-1beta (IL-1β) secretion by polymorphonuclear leukocytes (PMNs) were inves...
Context: The present study was planned to investigate the effect of absorption enhancers on the microstructure of Losartan potassium gel and hence its influence on the diffusion of Losartan potassium...
Aim: The concomitant use of angiotensin II receptor blocker (ARB) with low doses of hydrochlorothiazide (HCTZ) may provide additional antihypertensive activity. HCTZ induces hypokalemia and hyperglyce...
A new, simple, sensitive and selective spectrofluorimetric method for the determination of Hydrochlorothiazide was developed in acetonitrile at pH 6.2. The Hydrochlorothiazide can remarkably enhance t...