23:56 EDT 26th August 2014 | BioPortfolio
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AKORN BALANCED SALT SOLUTION is a sterile physiological solution containing calcium chloride (CaCl•2HO), magnesium chloride (MgCl•6HO), potassium chloride (KCl), sodium acetate (CHNaO•3HO), sodium chloride (NaCl) and sodium citrate (CHNaO•2HO). This solution is isotonic to ocular tissue and contains electrolytes required for normal cellular metabolic functions. Each 1 mL contains:

7.0 pH and 300 mosm/kg osmolality.

Calcium Chloride (MW 147.02) 0.48 mg
Magnesium Chloride (MW 203.31) 0.30 mg
Potassium Chloride (MW 74.56) 0.75 mg
Sodium Acetate (MW 136.08) 3.90 mg
Sodium Chloride (MW 58.44) 6.40 mg
Sodium Citrate (MW 294.10) 1.70 mg
Hydrochloric Acid and/or Sodium Hydroxide added to adjust pH.
Water for Injection

Balanced Salt Solution is an isotonic solution for use in irrigating tissues of the eyes.

For use as an extraocular and intraocular irrigating solution during ocular surgical procedure involving perfusion of the eye with an expected maximum duration of less than 60 minutes.

There are no specific contraindications for this preparation.

Open under aseptic conditions only.

Prior to use, check the following: tip should be firmly in place, irrigating needle should be properly seated; squeeze out several drops before inserting into anterior chamber. The needle should be removed from the anterior chamber prior to releasing pressure to prevent suction.

Studies suggest that intraocular irrigating solutions which are iso-osmotic with normal aqueous fluids should be used with caution in diabetic patients undergoing vitrectomy since intraoperative lens changes have been observed.

There have been reports of corneal clouding or edema following ocular surgery in which Balanced Salt Solution (Sterile Irrigating Solution) was used as an irrigating solution.

Irrigation or any trauma to the corneal endothelium may result in corneal swelling or bullous keratopathy.

Postoperative inflammatory reactions as well as incidents of corneal edema and corneal decompensation have been reported.

The adaptor plug is designed to accept an irrigating needle. Tissues may be irrigated by attaching the needle to the bottle as explained below. External irrigation may be done without the irrigating needle.

18 mL bottle, NDC 17478-920-19

Store at 20° to 25°C (68° to 77°F) [see USP Controlled Room Temperature]. Avoid exposure to excessive heat and do not allow to freeze.

Akorn Lake Forest, IL 60045

BS00NRev. 05/08

Principal Display Panel Text for Container Label:

NDC 17478-920-19 Akorn Logo



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18 mL Sterile Single Dose Bottle

IMAGE bal00-0002-01.jpg

Principal Display Panel Text for Carton Label:

NDC 17478-920-19 Akorn Logo


30 Sterile Single Dose Bottles (18 mL each)


IMAGE bal00-0002-02.jpg


Akorn, Inc.

Active Ingredients


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Bss [Alcon Laboratories, Inc.]

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To investigate the bactericidal effect of 0.025% povidone-iodine in Balanced Salt Solution PLUS (0.025% PI-BSS PLUS) and its use in vitrectomy for postoperative endophthalmitis.

Study of morbidity pattern among salt workers in marakkanam, Tamil Nadu, India.

Salt workers are exposed to occupational hazards like contact with salt crystals and brine, physical stress, sunlight and glare due to sunlight reflected by salt crystals. Very few studies have docume...

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Reducing particle size of salt to approximately 1.5 μm would increase its surface area, leading to increased dissolution rate in saliva and more efficient transfer of ions to taste buds, and hence, p...

Reduced dietary salt for the prevention of cardiovascular disease.

This is an update of a Cochrane review that was first published in 2011 of the effects of reducing dietary salt intake, through advice to reduce salt intake or low-sodium salt substitution, on mortali...

Consumption and Sources of Dietary Salt in Family Members in Beijing.

In China, few people are aware of the amount and source of their salt intake. We conducted a survey to investigate the consumption and sources of dietary salt using the "one-week salt estimation metho...


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