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Medical treatment of pericarditis during pregnancy.

Summary of "Medical treatment of pericarditis during pregnancy."

We have followed 6 pregnancies in women affected by idiopathic pericarditis from 2002 to 2008, the largest reported clinical series. Four women were treated with aspirin 800 mg three times daily; in 3 women aspirin was gradually stopped at 20 weeks gestation, while in one case aspirin was continued till delivery. All the women were treated with prednisone, at low to moderate doses: 4 women with prednisone 10-2.5 mg daily during all the pregnancy, and 2 with prednisone starting from 25 mg daily only during the III trimester. Maternal mean age was 30.2 years, mean gestational age at delivery 38 weeks and mean birth weight 2839 g, with one infant small for gestational age. Five pregnancies were uneventful, while HELLP syndrome developed in the mother in which high-dose aspirin was continued till delivery, with rapid improvement after delivery. All the infants had a good outcome. No recurrences occurred during the pregnancies, while one mother had a recurrence 12 months after delivery, during a mean follow up of 21 months.

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Journal Details

This article was published in the following journal.

Name: International journal of cardiology
ISSN: 1874-1754
Pages: 413-4

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Medical and Biotech [MESH] Definitions

Inflammation of the PERICARDIUM from various origins, such as infection, neoplasm, autoimmune process, injuries, or drugs-induced. Pericarditis usually leads to PERICARDIAL EFFUSION, or CONSTRICTIVE PERICARDITIS.

INFLAMMATION of the sac surrounding the heart (PERICARDIUM) due to MYCOBACTERIUM TUBERCULOSIS infection. Pericarditis can lead to swelling (PERICARDIAL EFFUSION), compression of the heart (CARDIAC TAMPONADE), and preventing normal beating of the heart.

Conditions or pathological processes associated with pregnancy. They can occur during or after pregnancy, and range from minor discomforts to serious diseases that require medical interventions. They include diseases in pregnant females, and pregnancies in females with diseases.

First aid or other immediate intervention for accidents or medical conditions requiring immediate care and treatment before definitive medical and surgical management can be procured.

The absence of a useful purpose or useful result in a diagnostic procedure or therapeutic intervention. The situation of a patient whose condition will not be improved by treatment or instances in which treatment preserves permanent unconsciousness or cannot end dependence on intensive medical care. (From Ann Intern Med 1990 Jun 15;112(12):949)

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