Construction of a ferritin dimer by breaking its symmetry.
Summary of "Construction of a ferritin dimer by breaking its symmetry."
Ferritin has a mono-dispersed structure and biomineralization properties that allow it to form various kinds of nanoparticles and play an important role in modern nanotechnology. Independent nanoparticles synthesized in ferritin are valuable, but moreover a pair of nanoparticles can bring new properties different from those of the independent nanoparticles. In this study, by breaking ferritin's symmetry, we successfully produced ferritin dimers which provide real protein frameworks for nanoparticle dimer formation. Identical nickel hydro-oxide nanoparticle dimers were produced by simply biomineralizing ferritin dimers. The method presented here can produce multi-functional ferritin dimers with different kinds of nanoparticles.
Affiliation
Graduate School of Materials Science, Nara Institute of Science and Technology, Ikoma, Nara, Japan.
Journal Details
This article was published in the following journal.
Name: Nanotechnology
ISSN: 1361-6528
Pages: 445602
Links
- PubMed Source: http://www.ncbi.nlm.nih.gov/pubmed/20935356
- DOI: http://dx.doi.org/10.1088/0957-4484/21/44/445602
Medical and Biotech [MESH] Definitions
Nematoda
A class of unsegmented helminths with fundamental bilateral symmetry and secondary triradiate symmetry of the oral and esophageal structures. Many species are parasites.
Financing, Construction
Funding resources and procedures for capital improvement or the construction of facilities.
Facility Design And Construction
Architecture, exterior and interior design, and construction of facilities other than hospitals, e.g., dental schools, medical schools, ambulatory care clinics, and specified units of health care facilities. The concept also includes architecture, design, and construction of specialized contained, controlled, or closed research environments including those of space labs and stations.
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The protein components of a number of complexes, such as enzymes (APOENZYMES), ferritin (APOFERRITINS), or lipoproteins (APOLIPOPROTEINS).
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