Construction of a ferritin dimer by breaking its symmetry.
Summary of "Construction of a ferritin dimer by breaking its symmetry."
Ferritin has a mono-dispersed structure and biomineralization properties that allow it to form various kinds of nanoparticles and play an important role in modern nanotechnology. Independent nanoparticles synthesized in ferritin are valuable, but moreover a pair of nanoparticles can bring new properties different from those of the independent nanoparticles. In this study, by breaking ferritin's symmetry, we successfully produced ferritin dimers which provide real protein frameworks for nanoparticle dimer formation. Identical nickel hydro-oxide nanoparticle dimers were produced by simply biomineralizing ferritin dimers. The method presented here can produce multi-functional ferritin dimers with different kinds of nanoparticles.
Graduate School of Materials Science, Nara Institute of Science and Technology, Ikoma, Nara, Japan.
This article was published in the following journal.
- PubMed Source: http://www.ncbi.nlm.nih.gov/pubmed/20935356
- DOI: http://dx.doi.org/10.1088/0957-4484/21/44/445602
Medical and Biotech [MESH] Definitions
A class of unsegmented helminths with fundamental bilateral symmetry and secondary triradiate symmetry of the oral and esophageal structures. Many species are parasites.
Funding resources and procedures for capital improvement or the construction of facilities.
Facility Design And Construction
Architecture, exterior and interior design, and construction of facilities other than hospitals, e.g., dental schools, medical schools, ambulatory care clinics, and specified units of health care facilities. The concept also includes architecture, design, and construction of specialized contained, controlled, or closed research environments including those of space labs and stations.
Hospital Design And Construction
The architecture, functional design, and construction of hospitals.
The protein components of a number of complexes, such as enzymes (APOENZYMES), ferritin (APOFERRITINS), or lipoproteins (APOLIPOPROTEINS).
Enantiomorphic symmetry breaking of stirred samples of molten sodium chlorate is demonstrated, revealing the unexpected involvement of an achiral solid phase. The results should stimulate future compu...
A second-order phase transition is characterized by spontaneous symmetry breaking. The nature of the broken symmetry in the so-called "hidden-order" phase transition in the heavy-fermion compound URu(...
The transport behavior of paramagnetic particles on top of a ferrimagnetic garnet film is investigated in a modulated external magnetic field. Broken symmetries are required to direct the transport of...
Epidermal growth factor receptors (EGFRs) and their cytoplasmic tyrosine kinases play important roles in cell proliferation and signaling. The EGFR extracellular domain (sEGFR) forms a dimer upon the...
Molecular systems where several apparently equivalent charge separation pathways exist upon photoexcitation are presented. They encompass MQ(n) (n≥2) architectures, where M is a chromophore and Q an...
To determine whether D-Dimer testing, using the MDA D-Dimer assay, can be used to simplify the diagnostic process for pulmonary embolism (PE). This will be assessed by performing a cohort...
Fungal infections in immunocompromised patients occuring during construction activities in hospitals have repeatedly been reported. However, the question of a causal relation between cons...
The purpose of this study is to see if a blood test (D-dimer) is as precise as the CT scan for the detection of clots. A pulmonary embolism is an obstruction of the blood vessels in your...
Optimal duration of oral anticoagulant therapy in patients with recurrent episodes of venous thromboembolism (VTE) is a matter of debate and recommendations are based on inadequate evidenc...
The purpose of this study is to determine if the risk of recurrent venous thromboembolism (VTE) after stopping therapy is low and acceptable in patients with a first unprovoked proximal de...