Chitin, Chitosan and Derivatives for Wound Healing and Tissue Engineering.

06:00 EST 13th November 2010 | BioPortfolio

Summary of "Chitin, Chitosan and Derivatives for Wound Healing and Tissue Engineering."

Naturally derived polymers possess a number of properties beneficial to wound healing and tissue engineering. The polysaccharides chitin and chitosan appear to be suitable candidates for the preparation of dressing materials and scaffolds for tissue regeneration due to their unique structural, physico-chemical and functional properties. Functionalization of these biopolymers for improvement of properties such as solubility or introduction of active functions and blending with other intrinsically bioactive polymers has attracted considerable attention in recent years. Such modifications would allow going beyond traditional approaches for treatments of dermal injuries. This chapter is a critical review of the advances in chitin and chitosan functionalization for wound-healing and tissue-engineering applications.


Department of Chemical Engineering, Universitat Politécnica de Catalunya, Escola Universitária d'Enginyeria Tècnica Industrial, Colom 1, 08222, Terrassa, Spain.

Journal Details

This article was published in the following journal.

Name: Advances in biochemical engineering/biotechnology
ISSN: 1616-8542


DeepDyve research library

PubMed Articles [13145 Associated PubMed Articles listed on BioPortfolio]

Chitosan as a starting material for wound healing applications.

Chitosan and its derivatives have attracted great attention due to their properties beneficial for application to wound healing. The main focus of the present review is to summarize studies involving ...

Special Collection: Closing the Gaps in Skin Wound Healing.

Skin is the largest and most accessible organ in the body and any compromise in its integrity results in a healing cascade. Often, underlying pathologies hamper these cascades. A tissue-engineering ap...

The Effect of Mesenchymal Stem Cells and Chitosan Gel on Full Thickness Skin Wound Healing in Albino Rats: Histological, Immunohistochemical and Fluorescent Study.

Wound healing involves the integration of complex biological processes. Several studies examined numerous approaches to enhance wound healing and to minimize its related morbidity. Both chitosan and m...

Bioglass activated skin tissue engineering constructs for wound healing.

Wound healing is a complicated process and fibroblast is a major cell type that participates in the process. Recent studies have shown that bioglass (BG) can stimulate fibroblasts to secrete a multitu...

Wound healing and hyper-hydration: a counterintuitive model.

Winter's seminal work in the 1960s relating to providing an optimal level of moisture to aid wound healing (granulation and re-epithelialisation) has been the single most effective advance in wound ca...

Clinical Trials [2690 Associated Clinical Trials listed on BioPortfolio]

Efficacy and Safety of HEP-40 Chitosan for Mild to Moderately Elevated Cholesterol

Chitosan is a natural product that is produced commercially through the deacetylation of chitin, which is found in the exoskeleton of crustaceans. It has been suggested that chitosan has a...

Effect of miR-200b on Diabetic Foot Ulcers

This study aims to determine if elevated wound-edge endothelial miR-200b is a barrier to wound healing in diabetic patients. This study will enroll 60 Diabetic Foot Ulcer (DFU) patients wh...

Interest in the Use of Dressings With Honey for Wound Healing After Excision of Pilonidal Cyst

The management of pilonidal cysts is a skin excision and under deep skin. Scarring requires regular dressings (daily for 15 days and then every 48 hours) until complete healing. This heali...

Wound Healing In Diabetes (WHy) Study

This observational study aims to identify risk factors and molecular mechanisms of impaired wound healing, to guide better foot care in the diabetic population.

EktoTherix™ Regenerative Tissue Scaffold for Repair of Surgical Excision Wounds

The purpose of study is to assess the safety and performance of EktoTherix™ Tissue Repair Scaffold in the treatment of full-thickness, dermatologic wounds created by the surgical removal...

Medical and Biotech [MESH] Definitions

The application of a vacuum across the surface of a wound through a foam dressing cut to fit the wound. This removes wound exudates, reduces build-up of inflammatory mediators, and increases the flow of nutrients to the wound thus promoting healing.

A linear polysaccharide of beta-1->4 linked units of ACETYLGLUCOSAMINE. It is the second most abundant biopolymer on earth, found especially in INSECTS and FUNGI. When deacetylated it is called CHITOSAN.

The fibrous tissue that replaces normal tissue during the process of WOUND HEALING.

Deacetylated CHITIN, a linear polysaccharide of deacetylated beta-1,4-D-glucosamine. It is used in HYDROGEL and to treat WOUNDS.

Removal of degenerated and necrotic epithelium and underlying connective tissue of a periodontal pocket in an effort to convert a chronic ulcerated wound to an acute surgical wound, thereby insuring wound healing and attachment or epithelial adhesion, and shrinkage of the marginal gingiva. The term is sometimes used in connection with smoothing of a root surface or ROOT PLANING. (Jablonski; Illustrated Dictionary of Dentistry, 1982)

Quick Search

DeepDyve research library

Relevant Topic

Wound management
Anything that breaks the skin is a wound because when the skin is broken, there's a risk of germs getting into the body and causing an infection. Follow and track Wound Care News on BioPortfolio: Wound Car...

Searches Linking to this Article