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Naturally derived polymers possess a number of properties beneficial to wound healing and tissue engineering. The polysaccharides chitin and chitosan appear to be suitable candidates for the preparation of dressing materials and scaffolds for tissue regeneration due to their unique structural, physico-chemical and functional properties. Functionalization of these biopolymers for improvement of properties such as solubility or introduction of active functions and blending with other intrinsically bioactive polymers has attracted considerable attention in recent years. Such modifications would allow going beyond traditional approaches for treatments of dermal injuries. This chapter is a critical review of the advances in chitin and chitosan functionalization for wound-healing and tissue-engineering applications.
Department of Chemical Engineering, Universitat Politécnica de Catalunya, Escola Universitária d'Enginyeria Tècnica Industrial, Colom 1, 08222, Terrassa, Spain.
This article was published in the following journal.
Name: Advances in biochemical engineering/biotechnology
Chitosan, which is derived from a deacetylation reaction of chitin, has attractive antimicrobial activity. However, chitosan applications as a biocide are only effective in acidic medium due to its lo...
The present findings were aimed to develop an effective form of collagen - chitosan film to investigate the wound healing property in Wistar rats. Primarily, the acid-soluble collagen (ASC) isolated, ...
Collagen-based biomaterials are of the utmost importance for tissue engineering and regenerative medicine. The aims of the present investigation were to evaluate structural and rheological properties ...
Chitin and chitosan were obtained by chemical treatments of shrimp shells. Different particle sizes (50-1000μm) of the raw material were used to study its effect on size distribution, demineralizatio...
This article describes a chitosan-collagen composite membrane as corneal tissue-engineering biomaterials. The membrane was prepared by dissolving the chitosan into collagen with the weight ratio of 0,...
Chitosan is a natural product that is produced commercially through the deacetylation of chitin, which is found in the exoskeleton of crustaceans. It has been suggested that chitosan has a...
The management of pilonidal cysts is a skin excision and under deep skin. Scarring requires regular dressings (daily for 15 days and then every 48 hours) until complete healing. This heali...
This observational study aims to identify risk factors and molecular mechanisms of impaired wound healing, to guide better foot care in the diabetic population.
The purpose of study is to assess the safety and performance of EktoTherix™ Tissue Repair Scaffold in the treatment of full-thickness, dermatologic wounds created by the surgical removal...
This research is being done to increase knowledge about wound healing and different factors that may affect healing in burn patients.
The application of a vacuum across the surface of a wound through a foam dressing cut to fit the wound. This removes wound exudates, reduces build-up of inflammatory mediators, and increases the flow of nutrients to the wound thus promoting healing.
A linear polysaccharide of beta-1->4 linked units of ACETYLGLUCOSAMINE. It is the second most abundant biopolymer on earth, found especially in INSECTS and FUNGI. When deacetylated it is called CHITOSAN.
The fibrous tissue that replaces normal tissue during the process of WOUND HEALING.
Deacetylated CHITIN, a linear polysaccharide of deacetylated beta-1,4-D-glucosamine. It is used in HYDROGEL and to treat WOUNDS.
Removal of degenerated and necrotic epithelium and underlying connective tissue of a periodontal pocket in an effort to convert a chronic ulcerated wound to an acute surgical wound, thereby insuring wound healing and attachment or epithelial adhesion, and shrinkage of the marginal gingiva. The term is sometimes used in connection with smoothing of a root surface or ROOT PLANING. (Jablonski; Illustrated Dictionary of Dentistry, 1982)
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Anything that breaks the skin is a wound because when the skin is broken, there's a risk of germs getting into the body and causing an infection. Follow and track Wound Care News on BioPortfolio: Wound Car...