Influence of Smoking Habits on the GA/HbA1c Ratio in Patients with Type 1 Diabetes Mellitus.
Summary of "Influence of Smoking Habits on the GA/HbA1c Ratio in Patients with Type 1 Diabetes Mellitus."
Objective: To assess the influence of smoking on glycated albumin (GA) to hemoglobin A1c (HbA1c) ratio among type 1 diabetes mellitus (T1DM) patients. Subjects and Methods: Eighty-one T1DM patients (49 females, 32 males, mean age 48 +/- 18 years) were recruited, and data concerning GA/HbA1c ratio and smoking were collected. Results: The median levels of GA and HbA1c were 23.3 and 7.4%, respectively. Independent of age, sex and/or body mass index, the GA/HbA1c ratio in smokers was significantly lower than that in nonsmokers (3.0 vs. 3.3, p < 0.05). Conclusion: The data suggest that smoking might affect the GA/HbA1c ratio among T1DM patients.
Affiliation
Department of Clinical Laboratory Medicine, Jichi Medical University, Shimotsuke, Japan.
Journal Details
This article was published in the following journal.
Name: Medical principles and practice : international journal of the Kuwait University, Health Science Centre
ISSN: 1423-0151
Pages: 415-417
Links
- PubMed Source: http://www.ncbi.nlm.nih.gov/pubmed/20639670
- DOI: http://dx.doi.org/10.1159/000316385
Medical and Biotech [MESH] Definitions
Odds Ratio
The ratio of two odds. The exposure-odds ratio for case control data is the ratio of the odds in favor of exposure among cases to the odds in favor of exposure among noncases. The disease-odds ratio for a cohort or cross section is the ratio of the odds in favor of disease among the exposed to the odds in favor of disease among the unexposed. The prevalence-odds ratio refers to an odds ratio derived cross-sectionally from studies of prevalent cases.
Smoking Cessation
Discontinuation of the habit of smoking, the inhaling and exhaling of tobacco smoke.
Cognitive Dissonance
Motivational state produced by inconsistencies between simultaneously held cognitions or between a cognition and behavior; e.g., smoking enjoyment and believing smoking is harmful are dissonant.
Gonadal Dysgenesis, Mixed
A type of defective gonadal development in patients with a wide spectrum of chromosomal mosaic variants. Their karyotypes are of partial sex chromosome monosomy resulting from an absence or an abnormal second sex chromosome (X or Y). Karyotypes include 45,X/46,XX; 45,X/46,XX/47,XXX; 46,XXp-; 45,X/46,XY; 45,X/47,XYY; 46,XYpi; etc. The spectrum of phenotypes may range from phenotypic female through pseudohermaphrodite to phenotypic male, depending on the ratio in each gonad of 45,X primordial germ cells to those with normal 46,XX or 46,XY constitution.
Leukocyte Adherence Inhibition Test
Test for cell-mediated antitumor immunity and related serum blocking factors based on the finding that leukocytes from cancer patients, but not from controls, when mixed in vitro with antigenic extracts of tumors of the same histological type, undergo a diminution in their normal adherence to glass surfaces. Sera from tumor-bearing patients block the LAI reaction of their own leukocytes or those of other patients with the same type of tumor.
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