Evaluation of non-ampullary duodenal polyps: Comparison of non-neoplastic and neoplastic lesions.
Summary of "Evaluation of non-ampullary duodenal polyps: Comparison of non-neoplastic and neoplastic lesions."
AIM:
To evaluate duodenal polyps, divided into non-neoplastic and neoplastic lesions. In addition, the clinical characteristics of duodenal hyperplastic polyps are determined.
METHODS:
We analyzed medical records of 50 114 consecutive patients submitted to for first diagnostic esophago-gastroduodenoscopy between January 2004 and December 2009. We excluded lesions on the ampulla of Vater and submucosal tumors. We studied 510 cases that were diagnosed endoscopically with duodenal polyps and enrolled a total of 221 cases that had undergone tissue biopsy. We analyzed the differences between non-neoplastic and neoplastic lesions, and determined the clinical features of duodenal hyperplastic polyps.
RESULTS:
Non-neoplastic lesions were found in 196 patients and neoplastic lesions in 25 patients. On univariate analysis, there were significant differences in shape, location, and size. Polyps more than 10 mm in diameter or polyps in the second portion had independent risk factors for being neoplastic lesions, as identified by multivariate analysis. In 23 cases of hyperplastic polyps (79.3%), they were accompanied by gastro-duodenal pathology, which was possibly associated with Helicobacter pylori.
CONCLUSION:
Polyps of more than 10 mm or polyps in the second portion of the duodenum should be evaluated by histological examination.
Affiliation
Department of Internal Medicine, College of Medicine, The Catholic University of Korea, St. Vincent's Hospital Ji-dong, Paldal-gu, Suwon Si, Gyeonggi-Do 442-723, South Korea. jwchulkr@yahoo.co.kr.
Journal Details
This article was published in the following journal.
Name: World journal of gastroenterology : WJG
ISSN: 1007-9327
Pages: 5474-5480
Links
- PubMed Source: http://www.ncbi.nlm.nih.gov/pubmed/21086567
- DOI: http://dx.doi.org/
Medical and Biotech [MESH] Definitions
Intestinal Polyposis
The growth of INTESTINAL POLYPS. Growth processes include neoplastic (ADENOMA and CARCINOMA) and non-neoplastic (hyperplastic, mucosal, inflammatory, and other polyps).
Reticuloendotheliosis, Avian
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Pregnancy Complications, Neoplastic
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Cysts
Any fluid-filled closed cavity or sac that is lined by an EPITHELIUM. Cysts can be of normal, abnormal, non-neoplastic, or neoplastic tissues.
Gene Expression Regulation, Neoplastic
Any of the processes by which nuclear, cytoplasmic, or intercellular factors influence the differential control of gene action in neoplastic tissue.
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