Diffusion tensor imaging of the kidney at 3 Tesla: normative values and repeatability of measurements in healthy volunteers.
Summary of "Diffusion tensor imaging of the kidney at 3 Tesla: normative values and repeatability of measurements in healthy volunteers."
To evaluate the feasibility of renal diffusion tensor imaging and determine the normative fractional anisotropy and apparent diffusion coefficient values at 3 Tesla MRI using parallel imaging and free breathing technique. MATERIALS AND
A total of 52 young healthy volunteers with no history of renal disease were included in the study. MRI examinations were performed with 3 Tesla MRI equipment, using six-channel phased array SENSE Torso coil. In all subjects, T2-weighted turbo spin echo and diffusion tensor imaging using single shot echo planar imaging sequences were obtained in the coronal plane with free breathing. Field of view, slice thickness and slice gap values were identical for both sequences for anatomic correlation during analysis of diffusion tensor imaging data. Parallel imaging method was used with a SENSE factor of 2. Diffusion tensor parameters of the cortex and medulla were determined and the intra- and inter-observer measurement variances were calculated.
The mean fractional anisotropy of the medulla was significantly higher than that of the cortex, whereas the mean apparent diffusion coefficient of the medulla was lower when compared with that of the cortex. According to the two-sided paired samples Student's t test, the intra- and inter-observer measurements correlated well.
This study shows the feasibility of renal diffusion tensor imaging and repeatibility of diffusion tensor parameter measurements in 3 Tesla MRI.
Department of Radiology, Yeditepe University School of Medicine, Istanbul, Turkey.
This article was published in the following journal.
Name: Diagnostic and interventional radiology (Ankara, Turkey)
- PubMed Source: http://www.ncbi.nlm.nih.gov/pubmed/21108183
- DOI: http://dx.doi.org/10.4261/1305-3825.DIR.3892-10.1
The purpose of this study was to evaluate to which degree investment of acquisition time in more encoding directions leads to better image quality (IQ) and what influence the number of encoding direct...
To compare the precision of measuring the pennation angle and fiber length in the vastus lateralis (VL) using two distinctly different diffusion tensor imaging (DTI) sequences.
To develop a diffusion tensor imaging (DTI) protocol for assessing the sural nerve in healthy subjects.
To study the potential of diffusion tensor imaging (DTI) to serve as a biomarker for radiation-induced brain injury during chemo-radiotherapy (RT) treatment.
Intramedullary spinal cord neoplasms (ISCN) in children provide diagnostic, treatment and management dilemmas. Resection results in the best chance for disease control, but the greatest risk of neurol...
The researchers' objective is to use diffusion-tensor imaging (DTI) to evaluate infants diagnosed with cerebral white matter injury during the neonatal period and identify antenatal risk f...
Focal cortical dysplasia (FCD) is a common finding in epilepsy surgery in pediatric patients. Children with intractable epilepsy would have extensive tests to identify the cause of epilep...
This study aims to validate magnetic resonance imaging and diffusion tensor imaging (MRI/ DTI) analysis as a non-invasive method for the assessment of myelinated nerve fibers loss in diab...
RATIONALE: New diagnostic procedures, such as 3 Tesla magnetic resonance imaging (MRI), may help find bladder cancer and learn the extent of disease. PURPOSE: This clinical trial is study...
This study is designed to learn about early brain development in children with Krabbe disease, and to use diffusion tensor imaging as an early diagnostic tool to identify newborns at risk ...
Medical and Biotech [MESH] Definitions
The use of diffusion ANISOTROPY data from diffusion magnetic resonance imaging results to construct images based on the direction of the faster diffusing molecules.
A diagnostic technique that incorporates the measurement of molecular diffusion (such as water or metabolites) for tissue assessment by MRI. The degree of molecular movement can be measured by changes of apparent diffusion coefficient (ADC) with time, as reflected by tissue microstructure. Diffusion MRI has been used to study BRAIN ISCHEMIA and tumor response to treatment.
The use of molecularly targeted imaging probes to localize and/or monitor biochemical and cellular processes via various imaging modalities that include RADIONUCLIDE IMAGING; ULTRASONOGRAPHY; MAGNETIC RESONANCE IMAGING; fluorescence imaging; and MICROSCOPY.
The complete summaries of the frequencies of the values or categories of a measurement made on a group of items, a population, or other collection of data. The distribution tells either how many or what proportion of the group was found to have each value (or each range of values) out of all the possible values that the quantitative measure can have.
The tendency of a gas or solute to pass from a point of higher pressure or concentration to a point of lower pressure or concentration and to distribute itself throughout the available space. Diffusion, especially FACILITATED DIFFUSION, is a major mechanism of BIOLOGICAL TRANSPORT.