Pathology: Does nodal micrometastasis impact outcome in biliary cancer?
Summary of "Pathology: Does nodal micrometastasis impact outcome in biliary cancer?"
No Summary Available
Affiliation
Department of Transplantation and Hepatobiliary and Pancreatic Surgery, Churchill Hospital, Headington, Oxford OX3 7LJ, UK.
Journal Details
This article was published in the following journal.
Name: Nature reviews. Clinical oncology
ISSN: 1759-4782
Pages: 680-1
Links
- PubMed Source: http://www.ncbi.nlm.nih.gov/pubmed/21116239
- DOI: http://dx.doi.org/10.1038/nrclinonc.2010.184
Medical and Biotech [MESH] Definitions
Biliary Tract Neoplasms
Tumors or cancer in the BILIARY TRACT including the BILE DUCTS and the GALLBLADDER.
Nodal Protein
The founding member of the nodal signaling ligand family of proteins. Nodal protein was originally discovered in the region of the mouse embryo primitive streak referred to as HENSEN'S NODE. It is expressed asymmetrically on the left side in chordates and plays a critical role in the genesis of left-right asymmetry during vertebrate development.
Biliary Fistula
Abnormal passage in any organ of the biliary tract or between biliary organs and other organs.
Left-right Determination Factors
Signaling ligands that act in opposition to NODAL PROTEIN. During vertebrate development they regulate the degree of left-right asymmetry by controlling the spatiotemporal influence of NODAL PROTEIN.
Carcinoma, Lobular
A infiltrating (invasive) breast cancer, relatively uncommon, accounting for only 5%-10% of breast tumors in most series. It is often an area of ill-defined thickening in the breast, in contrast to the dominant lump characteristic of ductal carcinoma. It is typically composed of small cells in a linear arrangement with a tendency to grow around ducts and lobules. There is likelihood of axillary nodal involvement with metastasis to meningeal and serosal surfaces. (DeVita Jr et al., Cancer: Principles & Practice of Oncology, 3d ed, p1205)
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