Impact of socioeconomic status on sexual maturation of Nigerian boys living with sickle cell anaemia.
Summary of "Impact of socioeconomic status on sexual maturation of Nigerian boys living with sickle cell anaemia."
Assessment of sexual maturation of children continues to have great relevance in monitoring their overall development. The interplay between innate disease characteristics and environmental modifiers such as socioeconomic status is not clearly understood among children with sickle cell anaemia (SCA).
To evaluate impact of socioeconomic status on sexual development of children living with sickle cell anaemia.
A cross-sectional case-control study evaluating sexual maturation of male patients with SCA (subjects) compared with non-SCAs (controls) was done. Tanner staging and testicular volume (TV) assessment were used for evaluating sexual maturation among both groups matched for age and socioeconomic status. Pattern of sexual maturation was related to socioeconomic status.
Subjects demonstrated delay in onset and completion of sexual maturation compared to controls. Testicular volumes of subjects were smaller than controls but when related to Tanner staging showed no significant difference between both groups. Onset of puberty was earlier in children from higher socioeconomic classes though this was very modest and not statistically significant. Similarly children of higher classes showed slightly larger TVs compared with those from lower classes.
SCA patients continue to demonstrate delay in sexual maturation compared with controls with normal haemoglobin genotype. Higher socioeconomic status showed a slight improvement on sexual maturation. This should provide a strong basis for advocacy to improve the welfare of families of children living with SCA as a worthwhile measure to improve their development and overall outlook. A larger study of a prospective nature is highly indicated.
Department of Paediatrics, University of Nigeria Teaching Hospital, Enugu, Nigeria; Department of Pediatrics, The Brooklyn Hospital Center, Brooklyn, NY, USA.
This article was published in the following journal.
Name: Hematology (Amsterdam, Netherlands)
- PubMed Source: http://www.ncbi.nlm.nih.gov/pubmed/21114905
- DOI: http://dx.doi.org/10.1179/102453310X12647083621209
The inverse association between socioeconomic status and cardiovascular disease is well documented. We examined whether the impact of health counselling on cardiovascular risk factors in middle-aged m...
In light of the consistent SES gradient in cardiovascular diseases, current research is focusing on possible pathways through which the socioeconomic status (SES) may impact health. Inflammatory proce...
People from lower socioeconomic groups have a higher risk of mortality. The impact of low socioeconomic status on survival among older adults with dementia and depression remains unclear.
The inverse relation between socioeconomic status and cardiovascular disease is well established. However, few studies have investigated socioeconomic status assessed repeatedly during adulthood in re...
Dating violence during adolescence negatively influences concurrent psychosocial functioning, and has been linked with an increased likelihood of later intimate partner violence. Identifying who is mo...
Originally from 1991 to 1991, to test the hypothesis that differences in hypertension prevalence in Nigerian workers were primarily related to differences in socioeconomic status (SES). A...
To investigate the inverse association between socioeconomic status (SES) and cardiovascular disease (CVD) in the Atherosclerosis Risk in Communities (ARIC) Study cohort.
The Impact of the "Nutrition Enrichment and Healthy Living Model" ( NEHLM) on Diet Quality, Physical Activity and Dental Health Among Children From Socioeconomically Disadvantaged Families in Beer Sheva
Childhood socioeconomic status (SES) is related to poor physical health, obesity, elevated cardiovascular risk factors and iron deficiency anemia. We plan to offer a comprehensive framewor...
To examine potential differences in the prevalence and pattern of risk factors for coronary heart disease in a sample of 500 self-identified lesbians and 500 heterosexual women, matched fo...
The primary objective of this study is to investigate whether bicalutamide given in combination with anastrozole once daily for 12 months is effective in treating testotoxicosis in boys. T...
Medical and Biotech [MESH] Definitions
Development of SEXUAL MATURATION in boys and girls at a chronological age that is 2.5 standard deviations below the mean age at onset of PUBERTY in the population. This early maturation of the hypothalamic-pituitary-gonadal axis results in sexual precocity, elevated serum levels of GONADOTROPINS and GONADAL STEROID HORMONES such as ESTRADIOL and TESTOSTERONE.
The lack of development of SEXUAL MATURATION in boys and girls at a chronological age that is 2.5 standard deviations above the mean age at onset of PUBERTY in a population. Delayed puberty can be classified by defects in the hypothalamic LHRH pulse generator, the PITUITARY GLAND, or the GONADS. These patients will undergo spontaneous but delayed puberty whereas patients with SEXUAL INFANTILISM will not.
The processes of anatomical and physiological changes related to sexual or reproductive functions during the life span of a human or an animal, from FERTILIZATION to DEATH. These processes include SEX DIFFERENTIATION; SEXUAL MATURATION; and changes during AGING.
Achievement of full sexual capacity in animals and in humans.
The health status of the family as a unit including the impact of the health of one member of the family on the family as a unit and on individual family members; also, the impact of family organization or disorganization on the health status of its members.