Clinical and Histopathologic Correlation of an Eruption Secondary to Taxotere.

02:02 EDT 28th May 2015 | BioPortfolio

Summary of "Clinical and Histopathologic Correlation of an Eruption Secondary to Taxotere."

Eruptions in cancer patients may signal life-threatening infections, cutaneous metastases or reactions to chemotherapeutic agents. Distinguishing between these processes is essential to correctly treat the patient. The authors present a patient with a diffuse eruption that was initially believed to be infectious in etiology. Temporal correlation with administration of Taxotere (docetaxel, sanofi aventis, Bridgewater, NJ) as well as histologic and microbiologic data established the eruption as a reaction to this medication. It is important to recognize this eruption (as well as others similar to it). The authors present clinical and histopathologic information to help clinicians identify reactions to this type of chemotherapy.

Affiliation

West Palm Beach and Jupiter, FL.

Journal Details

This article was published in the following journal.

Name: Journal of drugs in dermatology : JDD
ISSN: 1545-9616
Pages: 1534-1535

Links

PubMed Articles [24965 Associated PubMed Articles listed on BioPortfolio]

Histopathology of Rhinophyma - a clinical-histopathologic correlation.

Whereas early rhinophyma is histopathologically thought to resemble fully developed rosacea, a fibromatous variant has previously been described for severe rhinophyma. In terms of clinical characteris...

Neutrophilic Panniculitis: Algorithmic Approach to a Heterogeneous Group of Disorders.

Context.-Neutrophilic panniculitis encompasses an etiologically and morphologically heterogeneous group of disorders. Correct histopathologic diagnosis is important in identifying certain systemic dis...

Large eruption complex odontome in a Saudi patient.

Odontomas are odontogenic tumors formed of various dental tissues. They are classified into: central odontomas that are common, eruption odontomas that are rare with only 23 cases reported to date, an...

Correlation of chemokine receptor CXCR4 mRNA in primary cutaneous melanoma with established histopathologic prognosticators and the BRAF status.

Dysregulation of the chemokine receptor CXCR4 is relevant in melanoma progression, and the CXCR4/CXCL12 axis has been shown to activate cell cycle progression and malignant cell migration through stim...

Stereoselective synthesis of 4-substituted-cyclic sulfamidate-5-carboxylates by asymmetric transfer hydrogenation accompanied by dynamic kinetic resolution and applications to concise stereoselective syntheses of (-)-epi-cytoxazone and the taxotere side-chain.

Dynamic kinetic resolution driven, asymmetric transfer hydrogenation reactions of cyclic sulfamidate imine-5-carboxylate esters were developed. Applications of the new methodology to stereoselective s...

Clinical Trials [2141 Associated Clinical Trials listed on BioPortfolio]

Neoadjuvant Taxotere

The purposes of this study are to better understand how Taxotere causes tumors to become smaller and to find out how effective Taxotere is in treating the type of breast cancer that you ha...

A Phase III Study of the Efficacy of Taxotere/Aptosyn Versus Taxotere/Placebo in Non-Small Cell Lung Cancer Patients

Taxotere has been approved by the FDA and is considered a standard treatment for patients with lung cancer who have failed prior platinum-containing regimens. The main purpose of this res...

Taxotere/Temodar/Cisplatin Study in Melanoma Patients

Primary Objective: 1. To determine the maximum tolerated dose of chemotherapy using Taxotere, Temodar, Cisplatin (TTC) in patients with metastatic melanoma. Secondary Objectives: ...

Complement Regulatory Proteins Expression and Clinical Response in Rheumatoid Arthritis (RA) Patients Treated With Rituximab

There is a correlation between the CD55, CD59, CD35 and CD46 expression on B lymphocytes of patients before and after treatment with rituximab and the level of depletion and repopulation t...

Phase II Trial Comparing ABI-007 to Taxotere in First Line Therapy of Patients With Stage IV Breast Cancer

This is an open-label study conducted at study sites in Russia and the Ukraine comparing the toxicity and antitumor activity of ABI-007 to Taxotere.

Medical and Biotech [MESH] Definitions

Conditions which feature clinical manifestations resembling primary Parkinson disease that are caused by a known or suspected condition. Examples include parkinsonism caused by vascular injury, drugs, trauma, toxin exposure, neoplasms, infections and degenerative or hereditary conditions. Clinical features may include bradykinesia, rigidity, parkinsonian gait, and masked facies. In general, tremor is less prominent in secondary parkinsonism than in the primary form. (From Joynt, Clinical Neurology, 1998, Ch38, pp39-42)

An abnormality in the direction of a TOOTH ERUPTION.

The emergence of a tooth from within its follicle in the ALVEOLAR PROCESS of the MAXILLA or MANDIBLE into the ORAL CAVITY. (Boucher's Clinical Dental Terminology, 4th ed)

The complement of teeth in the jaws after the eruption of some of the permanent teeth but before all the deciduous teeth are absent. (Boucher's Clinical Dental Terminology, 4th ed)

A disseminated vesicular-pustular eruption caused by the herpes simplex virus (HERPESVIRUS HOMINIS), the VACCINIA VIRUS, or Varicella zoster (HERPESVIRUS 3, HUMAN). It is usually superimposed on a preexisting, inactive or active, atopic dermatitis (DERMATITIS, ATOPIC).

Search BioPortfolio:
Loading
Advertisement

Relevant Topic

Prostate Cancer
Latest News Clinical Trials Research Drugs Reports Corporate
Prostate cancer (cancer de prostata) Prostate cancer (cancer de prostata) is a form of cancer that develops in the prostate, a gland in the male reproductive system. Most prostate cancers are slow growing; however, there are cases of aggressive prostat...

Advertisement

Searches Linking to this Article