The stem cell "tunnel" effect.

10:22 EST 27th February 2015 | BioPortfolio

Summary of "The stem cell "tunnel" effect."

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Center for Cell and Gene Therapy, Baylor College of Medicine, Houston, Texas, USA.

Journal Details

This article was published in the following journal.

Name: Molecular therapy : the journal of the American Society of Gene Therapy
ISSN: 1525-0024
Pages: 2043-4


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Medical and Biotech [MESH] Definitions

Methods of implanting a CELL NUCLEUS from a donor cell into an enucleated acceptor cell. Often the nucleus of a somatic cell is transferred into a recipient OVUM or stem cell (STEM CELLS) with the nucleus removed. This technology may provide means to generate autologous diploid pluripotent cell for therapeutic cloning, and a model for studying NUCLEAR REPROGRAMMING in embryonic stem cells. Nuclear transfer was first accomplished with frog eggs (RANA PIPIENS) and reported in 1952.

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The malignant stem cells of TERATOCARCINOMAS, which resemble pluripotent stem cells of the BLASTOCYST INNER CELL MASS. The EC cells can be grown in vitro, and experimentally induced to differentiate. They are used as a model system for studying early embryonic cell differentiation.

Experimentation on STEM CELLS and on the use of stem cells.

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