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Celiac Disease with Splenic Calcifications.

Summary of "Celiac Disease with Splenic Calcifications."

Celiac disease is an immune mediated enteropathy due to irreversible gluten sensitivity. It has protean manifestations involving gastrointestinal (GI) as well as non GI manifestations. Calcifications in the cerebral cortex are well defined entity in celiac disease known as CEC syndrome (Celiac disease, Epilepsy and Cerebral Calcification). Calcification has not been described in any other organ. Splenic calcifications are a rare manifestation in childhood. The authors are reporting a case of celiac disease with multiple foci of calcification in the spleen without evidence of cerebral calcification.

Affiliation

Department of Pediatrics, Lady Hardinge Medical College, New Delhi, India, dranugulati@gmail.com.

Journal Details

This article was published in the following journal.

Name: Indian journal of pediatrics
ISSN: 0973-7693
Pages:

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Medical and Biotech [MESH] Definitions

The largest branch of the celiac trunk with distribution to the spleen, pancreas, stomach and greater omentum.

The arterial trunk that arises from the abdominal aorta and after a short course divides into the left gastric, common hepatic and splenic arteries.

A complex network of nerve fibers including sympathetic and parasympathetic efferents and visceral afferents. The celiac plexus is the largest of the autonomic plexuses and is located in the abdomen surrounding the celiac and superior mesenteric arteries.

The spontaneous transplantation of splenic tissue to unusual sites after open splenic trauma, e.g., after automobile accidents, gunshot or stab wounds. The splenic pulp implants appear as red-blue nodules on the peritoneum, omentum, and mesentery, morphologically similar to multifocal pelvic endometriosis. (Segen, Dictionary of Modern Medicine, 1992)

Simple protein, one of the prolamines, derived from the gluten of wheat, rye, etc. May be separated into 4 discrete electrophoretic fractions. It is the toxic factor associated with CELIAC DISEASE.

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